New strategies and concepts for hazard and risk assessment of chemicals are being developed in different research projects at Fraunhofer ITEM. The focus here is on human-relevant, non-animal methods such as in-vitro tests and in-silico computational tools.
An important starting point for avoiding animal testing in chemical safety assessment is the use of existing data for a group of “similar” substances and the use of read-across.
These approaches have been investigated at Fraunhofer ITEM in several publicly funded projects (e.g. in EU projects such as DETECTIVE within the SEURAT research cluster and the project EU-ToxRisk under the Horizon 2020 program).