Publicly funded research projects

National

Bavarian Ministry of Economic Affairs, Regional Development and Energy

Further development of Fraunhofer ITEM in Regensburg

 

Bayern Innovativ, funding program "Biomedical Engineering"

Project: KrEiBl

Method for blood-based cancer diagnosis at the single-cell level: molecular analysis of single cells

 

Deutsche Krebshilfe (German Cancer Aid) – Priority Program “Translational Oncology”

DETECT CTC: Detection and molecular characterization of circulating tumor cells and cell-free nucleic acids in advanced breast cancer in the context of tumor heterogeneity

 

DFG – German Research Foundation

Selection and adaptation during metastatic cancer progression. FOR 2127, project no. 242727105

Designing nanoparticle-based inhaled antibiotics for the treatment of cystic fibrosis associated biofilms and infections and in vivo studies in a rat model. Project no. 256755002

Identification of tumor-specific peptides for adjuvant immunotherapy of melanoma patients without distant metastasis. Project no. 320058447

 

Federal Environment Agency

Relevance of physiological and anthropometric parameters for the standardization and assessment of human biomonitoring results. R&D project 3716 62 214 0

 

Federal Institute for Occupational Safety and Health (BAuA)

Mode of toxic action of nanocarbons. Research project F 2376

 

Federal Joint Committee/Innovation Committee

PTmHBP – Practicability testing of the magistral production of bacteriophages for the therapy of septic infections of the lower extremity (PhagoFlow)

 

Federal Ministry for Economic Affairs and Energy, central innovation program for SMEs

Development of an ex-vivo rat lung model for quality assurance of surfactant batches without the need to simulate asphyxia

 

Federal Ministry of Education and Research (BMBF) action plan for individualized medicine, funding area “Innovations for individualized medicine”

Collaborative project: TurbiCAR

UniCAR-based treatment of CD19-positive lymphoblastic leukemia – subproject “Production of the anti-CD19 target module”

 

Federal Ministry of Education and Research (BMBF) framework program “Gesundheitsforschung” (health research)

Collaborative research project: 4-IN

Insect-derived inhalable inhibitors of bacterial virulence for treating lung infections

 

Collaborative research project: Phage4Cure

Developing bacteriophages as approved therapy against bacterial infections

 

Federal Ministry of Education and Research (BMBF) funding program “Alternatives to Animal Testing”

Project: InhalAb

Alternative models for testing of inhalable antibiotics

 

Federal Ministry of Education and Research (BMBF) funding program “Ersatz und Ergänzungsmethoden zum Tierversuch” (alternatives and complements to animal experiments)

Project: ExITox2 – Explain Inhalation Toxicity 2

Animal-free mechanism-based toxicity testing – predict toxicity after repeated-dose inhalation exposure by using a read-across approach

 

Federal Ministry of Education and Research (BMBF) funding program FlexMax: flexible active sensor matrix for medical applications

Use of sensor arrays in two different biomedical engineering systems:

sub-project "Sensorgesteuerte Atmungsüberwachung, Atmungstriggerung und Inhalation bei Frühgeborenen" (sensor-controlled breath monitoring, breath triggering, and inhalation in preterm infants)

 

Federal Ministry of Education and Research (BMBF) funding program "In-vitro Challenge"

ImmunAVATAR: Make your immune system great again (exploratory phase)

 

Federal Ministry of Education and Research (BMBF) funding program “Innovative Stammzelltechnologien für die individualisierte Medizin” (innovative stem cell technologies for individualized medicine)

Project: iCARE

Induced pluripotent stem cells for clinically applicable heart repair

 

Federal Ministry of Education and Research (BMBF) funding program "KMU-innovativ: Medizintechnik" (innovative SMEs: biomedical engineering)

Collaborative project: CTCbySCP

Development of a single cell printer-based method for marker-independent quantification and isolation of vital circulating tumor cells for diagnosis and personalized therapy

 

Federal Ministry of Education and Research (BMBF) funding program "NanoCare4.0 – application-safe material innovations"

Project: MetalSafety

Development of evaluation concepts for fibrous and granular metal compounds: bioavailability, toxicological efficacy profiles and comparative in vitro, ex vivo and in vivo studies

 

Project: NanoINHAL 

In-vitro test methods for airborne nanomaterials to investigate toxic potential and uptake after inhalation exposure using innovative organ-on-a-chip technology

 

Federal Ministry of Education and Research (BMBF) funding program “Sicherer Umgang mit synthetischen Nanomaterialien – Erforschung der Auswirkungen synthetischer Nanomaterialien auf den Menschen – NanoCare” (safe handling of synthetic nanomaterials – research on the impact of synthetic nanomaterials on human health - NanoCare)

Project: CaNTser 

Investigation of the toxic potency of carbon nanotubes following long time inhalation

 

Federal Office for Radiation Protection

Childhood leukemia – influence of the immune system on the development of the disease (experimental study in a suitable animal model)

 

German Center for Lung Research (DZL)

Allergy and asthma

Chronic obstructive pulmonary disease (COPD)

Diffuse parenchymal lung diseases (DPLD)

 

Lower Saxony Ministry of Science and Culture

Collaborative project: fibromics

Translating Omics studies into clinically relevant insights for lung fibrosis patients

International

EFSA project: Applying a tested procedure for the identification of potential emerging chemical risks in the food chain to the substances registered under REACH – REACH 2

 

EU project: ERA-Net TRANSCAN

Analysis of tumor evolution and identification of relapse-initiating tumor cells in non-small cell lung carcinoma

 

EU project: Eurostars TARGIT

Development of next-generation treatment for allergies: targeted glycan-allergen immunotherapy

 

EU project: ICONS – Integrated Cooperation On Nanotube Safety

An integrated testing strategy for mechanistically assessing the respiratory toxicity of functionalized multi-walled carbon nanotubes

 

EU project: IMI-eTranSafe

Enhancing translational safety assessment through integrative knowledge management

 

EU project: Immune Safety Avatar (imSAVAR)

Nonclinical mimicking of the immune system effects of immunomodulatory therapies

 

EU project: Marie Skłodowska-Curie Innovative Training Networks, Magicbullet :: Reloaded (Horizon 2020)

Development and employment of approaches for selective, targeted delivery of a panel of anticancer drugs for directed tumor therapy

 

EU project: MDOT (Medical Device Obligations Taskforce)

Establishment of a digital platform for simplified conformity assessment and testing of medical devices, including three demonstrator technologies: inhalation technology, 3D-printed neural implants, and coatings for orthopedic prostheses

 

EU project: PneumoNP

Nanotherapeutics to treat antibiotic-resistant Gram-negative infections of the lung

 

EU project: REMEDIA – RElation exposoME

DIseAse Impact of exposome on the course of lung diseases

 

EU project: SILIFE

Production of quartz powders with reduced crystalline silica toxicity

 

EU project: TBMED
An open innovation test bed for the development of high-risk medical devices

Translation of the quality-by-design approach of the pharmaceutical industry to biomedical engineering, using several medical devices as examples: bone defect reconstruction materials, keratoprosthesis, and nanoparticles for cancer treatment

 

EU project: ToxRisk (Horizon 2020)

An Integrated European ‘Flagship’ Programme Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st century

 

German Federal Ministry of Education and Research (BMBF) and Ministry of Research, Technology and Higher Education of the Republic of Indonesia (RISTEK): joint research program for the identification and use of natural substances from Indonesia for the development of new therapeutics

Collaborative research project: Triple-IN

Insect-derived anti-infectives from Indonesia