We are excited to be at this year’s SOT Annual Meeting and ToxExpo in Salt Lake City, Utah (USA), and will be very happy to share insights into our latest toxicology research with you.
Booth number: 817
Integration of Metabolite Data into Read-Across Assessments
Session: New Approach Methodology and Kinetic Modeling Approaches to Support Read-Across; Talk 1111
Tuesday, March 12, 8:35 a.m. - 9:05 a.m., Grand Ballroom E‚ Salt Palace Convention Center
Speaker: Dr. Sylvia Escher
Modeling of Bioavailable Concentration of N-Nitrosamines Built via Endogenous Mechanisms
Session: Nitrosamines: Mechanistic Evidence to Support Subclasses with Varying Mutagenic Potency; Talk 1209
Tuesday, March 12, 4:50 p.m. - 5:10 p.m., Grand Ballroom A‚ Salt Palace Convention Center
Speaker: Dr. Sylvia Escher
Evaluation of Clinical Chemistry Parameters: Which Factors Have an Impact?
Session: Is Less More? Reduction of Animal Use through Virtual Control Groups
Wednesday, March 13, 11:25 noon - 11:35 a.m., Room 250 A‚ Salt Palace Convention Center
Speaker: Dr. Sylvia Escher
ZET-O-MAP: Using Zebra Fish Transcriptome Data to Identify Biomarker for Teratogenic Compounds
Monday, March 11, 12:00 noon - 1:00 p.m., Room 155 B‚ Salt Palace Convention Center
Speaker: Matthias Wehr, Dr. Sylvia Escher, Dr. Marc Jacobs
Speaker-Spotlights and more details about the session
Safe-By-Design: Novel Approaches to Support Development of Safe Cosmetic Spray Products
Tuesday, March 12, 1:30 p.m. - 2:30 p.m., Room 155 B‚ Salt Palace Convention Center
Speaker: Dr. Katharina Schwarz, Dr. Detlef Ritter
Speaker-Spotlights and more details about the session
MUTAMIND: Genotoxicity of N-Nitrosamines
Wednesday, March 13, 10:30 a.m. - 11:30 a.m., Room 155 B‚ Salt Palace Convention Center
Speaker: Dr. Sylvia Escher, Anke Londenberg, Max Spänig, Dr. Kevin Cross
Salt Lake City, Utah (USA)
March 10, 2024 - March 14, 2024
English
Mutamind: Benchmark Dose Modeling of N-Nitrosamines based on comet and enhanced Ames assay data
Poster 3106/P210; Session: Genotoxicity/DNA Repair
Monday, March 11, 2024, 11:45 a.m. - 1:45 p.m.
Authors: A. Londenberg, S. Chang, M. A. Djuari, K. P. Cross, G. Johnson, M. Schulz, C. Ziemann, and S. Escher
Inhalation Toxicity Testing of the Cystein Cathepsin Inhibitor Aloxistatin for Treatment of Interstitial Lung Diseases
Poster 3007/P108; Session: Safety Assessment: Pharmaceutical-Drug Development I
Monday, March 11, 2024, 9:15 a.m. - 11:15 a.m.
Authors: D. Winterberg, G. Pohlmann, F. Dahlmann, A. Braun, A. Bitsch, T. Hansen, D. Schaudien, K. Blümlein, C. Peters, M. Hug, and S. Fähndrich
Interleukin-2 induces skin inflammation through CD25
Poster 3438/P605; Session: Immunotoxicity I
Monday, March 11, 2024, 9:15 a.m. - 11:15 a.m.
Authors: C. Sommer, J. N. Cohen, S. Dehmel, V. Neuhaus, D. Schaudien, A. Braun, K. Sewald, and M. D. Rosenblum
High-dose IL-2 reduces IL-2R signaling capacity in T cells
Poster 3439/P606; Session: Immunotoxicity I
Monday, March 11, 2024, 9:15 a.m. - 11:15 a.m.
Authors: C. Sommer, S. Jacob, S. Dehmel, V. Neuhaus, A. Braun, and K. Sewald
Adverse outcome pathways to unravel drug induced toxicity
Poster 3440/P607; Session: Immunotoxicity I
Monday, March 11, 2024, 9:15 a.m. - 11:15 a.m.
Authors: C. Sommer, V. Neuhaus, P. Gogesch, T. Flandre, A. Braun, S. Dehmel, and K. Sewald
ZET-O-MAP: Identify molecular drivers of teratogenic toxicants in time-resolved NAM data
Poster 3848/P351; Session: Developmental and Juvenile Toxicology
Tuesday, March 12, 2024, 11:45 a.m. - 1:45 p.m.
Authors: M. M. Wehr, B. Schultz, H. Witters, S. Remy, K. Hollanders, M. Jacobs, and S. Escher
Safe-by-design for biocidal spray products and applications: Does foam spraying provide a risk mitigation measure in terms of inhalation exposure?
Poster 4293/P868; Session: Respiratory Toxicology II
Tuesday, March 12, 2024, 11:45 a.m. - 1:45 p.m.
Authors: K. Schwarz, S. Hahn, K. Bluemlein, R. Hebisch, W. Koch, U. Poppek, U. Schlueter, and M. Krug
A 90-Day Nose-Only Inhalation study investigates Diniobium Pentaoxide as a novel Inert particulate dust
Poster 4310/P885; Session: Respiratory Toxicology II
Tuesday, March 12, 2024, 11:45 a.m. - 1:45 p.m.
Authors: G. Bruer, P. Janssen, D. Schaudien, M. Ramazanoglu, and O. Creutzenberg
Evaluating the deviation of the inhalTTC group's assessment on NOAEC/LOAEC values from those of the study authors
Poster 3617/P118; Session: Risk Assessment II
Tuesday, March 12, 2024, 11:45 a.m. - 1:45 p.m.
Authors: M. Schwarz-Zocher, A. M. Api, K. Joshi, S. Collins, G. Patlewicz, A. M. Bowden, F. Boislève, M. Singal, A. Giusti, N. Sadekar, and S. E. Escher
Safe-by-design: a case-study on a cosmetic spray product exploring a concept to support development and safety assessment
Poster 3515/P 753; Session: New Approach Methods: In Vitro I
Tuesday, March 12, 2024, 2:15 p.m. - 4:15 p.m.
Authors: D. Ritter, K. Schwarz, T. Hansen, A. Zifle, A. Fuchs, and R. Fautz
Physiological based kinetic modelling to assess the distribution of nitrosamine formed under physiological conditions
Poster 4430/P218; Session: Mathematical Modeling
Wednesday, March 13, 2024, 2:15 p.m. - 4:15 p.m.
Authors: M. Spänig, M. Vogel, T. Hansen, U. Deppenmeier, and S. Escher
MetalSafety: Toxicological effects of silver nanoparticles and nanowires observed across investigations in vitro, ex vivo, and in vivo
Poster 4730/P728; Session: Metals II
Wednesday, March 13, 2024, 2:15 p.m. - 4:15 p.m.
Authors: F. Schulz, T. Hansen, C. Ziemann, S. Reamon-Buettner, K. Grieger, K. Sewald, H. Fieguth, A. Hartwig, N. Honarvar, and A. Bitsch
Fraunhofer Institute for Toxicology and Experimental Medicine