Oral presentations
“Recent advances: TTC values for (non-)DNA reactive carcinogens and TTC for airborne compounds”
Session: “Thresholds of toxicological concern – recent developments”
Date and time: Sunday, September 18, 2022, 2:08 p.m. (CEST); Room: 0.15 Washington
Speaker: S. Escher
“Integration of PBK, in vitro kinetics, and NAMs into chemical risk assessment – challenges observed for inhalation exposure”
Session: “In vitro and in vivo kinetics in next-generation risk assessment: what, when and how?”
Date and time: Monday, September 19, 2022, 10 a.m. – 12 noon (CEST); Room: Auditorium 2
Speaker: S. Escher
Poster presentations
Poster Viewing 1
Monday, September 19, 2022, 1–2 p.m. (CEST), Expo Foyer/Brightlands Foyer
“Integration of adverse outcome pathways with knowledge graphs”
Session: “P01 – Adverse outcome pathways”
Authors: B. T. Schultz, M. Wehr, H. Witters, S. Escher, M. Jacobs
“Improving human relevance of Ames tests for regulatory use via in silico predicted metabolites”
Session: “P04 – Computational toxicology”
Authors: V. O. Jejeniwa, A. Schütte, S. Escher, M. Batke, J. vom Brocke
“Influence of extremely low frequency magnetic fields on the development of childhood leukemia – An experimental study in a susceptible Mouse Model”
Session: “P06 – Developmental & reproductive toxicology”
Authors: D. Sachno, S. Carstensen, F. Dahlmann, R. Kellner, M. Müller, K. Sewald, T. Tillmann, A. Bahr, M. Wleklinski, C. Dasenbrock, A. Bitsch
“Zet-O-Map – identify principal molecular drivers of (dys)morphogenesis in zebrafish”
Session: “P06 – Developmental & reproductive toxicology”
Authors: M. Wehr, B. Schulz, H. Witters, M. Jacobs, S. Escher
Poster Viewing 2
Tuesday, September 20, 2022, 1–2 p.m. (CEST), Expo Foyer/Brightlands Foyer
“Development of a non-target strategy for evaluation of potential biological effects of inhalable aerosols generated during purposeful room conditioning using an in vitro inhalation model”
Session: “P13 – Inhalation and respiratory toxicology”
Authors: D. Ritter, K. Schwarz, J. Knebel, T. Hansen, A. Zifle, A. Fuchs, R. Fautz
“Enhanced study design for acute inhalation studies with hydrophobic surface treated particles to reveal the issue of suffocation through strong agglomeration of particles in the nose of test animals”
Session: “P13 – Inhalation and respiratory toxicology”
Authors: G. Bruer, N. Krueger, K. Weber, N. Warfving, A. Vitali, J. Nolde, T. Schuster, O. Creutzenberg, P. Janssen, B. Wessely, M. Stintz, V. Moise, M. Kellert
“Design and application of a physiologically based kinetic (PBK) model for uptake of airborne particulates”
Session: “P17 – New Approach Methodologies (NAMs)”
Authors: N. Nowak, N. Sonnenschein, T. Hansen, D. Ritter, K. Blümlein, S. Escher, K. Schwarz
“Transcriptome Data to Substantiate the Assessment of Similar Mechanism of Actions in a Context of compound induced pulmonary fibrosis”
Session: “P20 – Omics approaches in toxicology”
Authors: C. Drake, W. Zobl, M. Wehr, J. Koschmann, D. De Luca, B. Kühne, H. Vrieling, J. Boei, T. Hansen, S. Escher
“Which scope of NAM testing is sufficient for hazard characterisation? An investigation based on transcriptomics data”
Session: “P20 – Omics approaches in toxicology”
Authors: W. Zobl, M. Wehr, C. Drake, J. Schimming, D. Pellegrino-Coppola, J. Blum, L. Santos Capinha, E. Davilo, P. Walker, B. Islam, L. Tolosa, P. Jennings, B. van Vugt-Lussenburg, J. Boei, M. Leist, B. van de Water, C. Fisher, S. Escher
“Identification of the applicability domain for the use of read-across in food safety – development of read-across concept integrating metabolites”
Session: “P22 – Risk prediction and assessment”
Authors: J. Irwan, E. Carnesecchi, G. Kass, A. Nathanail, N. Simetska, R. Kellner, S. Escher
Fraunhofer ITEM
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