Fraunhofer Institute for Toxicology and Experimental Medicine

Tigermücke in Nahansicht
© Alamy/F1 online
Die wärmeliebende Ägyptische Tigermücke gilt als Hauptüberträger von Gelbfieber, Dengue und Zika.

The race against viruses

Zoonoses are an increasing danger. Not all of them make us sick or can kill us. And yet: Corona will not remain an isolated case. "The production of vaccines must become significantly faster,” says Prof. Holger Ziehr.

more info

An exciting year 2020

Despite the fight against the pandemic, to which we have contributed with numerous research projects, we have also continued to develop other areas of research. Get an insight into interesting projects performed at Fraunhofer ITEM in 2020, our results, and the people behind all this.

more info
3D-Druck Kiefer
© Fraunhofer IMTE, Dr. Thomas Friedrich

High-Performance Center

The High-Performance Center Medical and Pharmaceutical Engineering, launched in March, creates a platform for research and the transfer of innovations into patient care.

more info
Fraunhofer ITEM #weknowhow
© Fraunhofer

Medical research on SARS-CoV-2

With our decades of experience in infection and airway research, drug development, biomedical engineering, and in the field of chemical risk assessment, we are meanwhile involved in numerous projects to fight the COVID-19 pandemic.

more info
Personalisierte Tumortherapie
© Fraunhofer ITEM, P. Reinig

What turns cells into killer cells?

Our Regensburg-based Division of Personalized Tumor Therapy is searching for approaches for novel diagnostics and personalized treatments in the fight against cancer.

more info
© Vasily Smirnov,

Bioinformatics and Digital Health

Processing large quantities of data is a major challenge of our era, in the life sciences in particular. The Project Group for Bioinformatics has been set up as an “Attract Group” at Fraunhofer ITEM.

more info
© -

Fighting bacteria with viruses

Fraunhofer scientists have joined forces with partners in the Phage4Cure project to explore alternatives to antibiotics.

more info

Fraunhofer ITEM: News

News / 6.9.2021

Safety of water resources

ZeroPM: Zero Pollution from persistent, mobile substances


Press Release / 13.7.2021

The heart complementing the lung

Minister Björn Thümler, Prof. Michael Manns, Prof. Ulrike Köhl, Prof. Norbert Krug, Prof. Thomas Thum in a panel discussion

Press Release / 12.8.2021

Tracking down aerosols

How do infectious aerosols spread in supermarkets, airplanes and other indoor spaces where many people come together? This is being investigated in the "AVATOR" project.

News / 27.8.2021

BMBF project

Aiming to protect lung tissue: investigating inhaled administration of angiotensin-(1-7) to COVID-19 patients with acute lung injury.


News / 6.7.2021

New publication

Rhinovirus-induced human lung tissue responses mimic COPD and asthma gene signatures.


News / 23.8.2021

New website

The High-Performance Center Medical and Pharmaceutical Engineering, launched in March 2021, has its own website now.

News / 22.7.2021

Single-cell microRNA sequencing

Publication in Nature Communications

News / 7.9.2021

TRAIN Academy

The curriculum "Translational Research and Medicine: From the Idea to the Product" is a two-year, career-oriented education program. The new class starts in October. 

Our services and expertise

Pioneers for sustainable health

Research at Fraunhofer ITEM is focused on human health – and this has been so for almost four decades.

The emphasis is on two aspects: firstly, on protecting health from potentially harmful, in particular airborne substances, be they gases, aerosols, particles, fibers, or nanomaterials, and secondly, on investigating and developing diagnostic and therapeutic approaches, both at the preclinical and clinical levels.

A special focus is on airway research.


Chemical Safety and Assessment


Translational Biomedical Engineering


Personalized Tumor Therapy

Focus of our research

The lung and airways are at the focus of our R&D activities. Furthermore, Fraunhofer ITEM engages in the development and manufacturing of biopharmaceuticals, tumor therapy, and translational biomedical engineering.


Bioinformatics and Digital Health

The Project Group for Bioinformatics improves the analysis of data collected in health research by using novel intelligent methods.


Fraunhofer ITEM

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM

Nikolai-Fuchs-Strasse 1
30625 Hannover

Phone +49 511 5350-0



EFSA training no. 1: Combined exposure to multiple chemicals

This online training course will provide a short review of the key terms, scientific basis for combined exposure risk assessment and approaches to assessing (eco)toxicology of combined exposures. Existing frameworks for risk assessment of combined exposure to multiple chemicals were evaluated by EFSA, resulting in a harmonized framework for risk assessment of combined exposure to multiple chemicals. The framework as published as EFSA Guidance in 2019 is based on the risk assessment steps (problem formulation, exposure assessment, hazard identification and characterization, and risk characterization including uncertainty analysis), with tiered and stepwise approaches for both whole-mixture approaches and component-based approaches.
Read more


EFSA training no. 2: Nanomaterials

This online training course will give guidance for best risk assessment practices of nanoscience and nanotechnologies applied in the agrochemical, food and feed sectors.
Read more


Day of Immune Research 2021

On "Day of Immune Research“ current topics in the field of immune-mediated diseases will be presented and discussed across disciplines and across institute borders. Current challenges are to be discussed and new solutions shall be jointly developed.
Read more


Training course: In-silico toxicology

This training course will introduce the participants to three different in-silico approaches for estimation of human health toxicological endpoints, namely QSAR models, read-across, and the TTC (threshold of toxicological concern) concept. The application of in-silico approaches in ecotoxicology will not be addressed in this course.
Read more

About Fraunhofer ITEM

The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is one of 75 institutes and research institutions of the Fraunhofer-Gesellschaft, the world’s leading applied research organization. Protecting man from health hazards in our industrialized world and contributing to the development of novel therapeutic approaches are the aims Fraunhofer ITEM is pursuing with its contract research. With a focus on airway research, our R&D portfolio includes three thematic areas: drug development, chemical safety, and translational biomedical engineering. In addition, our scientists in Regensburg do research in the field of personalized tumor therapy.

With a staff of 394 at its locations in Hannover, Braunschweig and Regensburg, the institute cooperates with industry, service providers, and public authorities in projects that drive economic development and serve the wider benefit of society.


More information about Fraunhofer ITEM