Fraunhofer Institute for Toxicology and Experimental Medicine

Fraunhofer ITEM: News


Press release / 1.2.2023

Improved wound healing

Fraunhofer researchers have succeeded in producing a bioresorbable membrane that is neither cytotoxic nor genotoxic.

BIOSYNTH project: DNA for data storage

Modular high-throughput microplatform for future mass data storage based on synthetic biology

Press release / 4.10.2022

Medical engineering to help assess nanoparticles

Fraunhofer scientists are developing the exposure device NanoCube whose integrated multi-organ chip detects interaction of nanoparticles and lung cells. 


News / 3.11.2022

Development of RNA-based drugs

Project iGUARD receives 1.5 million euros follow-up funding for rapid therapies against viral diseases.

News / 25.8.2022

Understanding Cabin Air Quality

The recently launched research project ”Cabin air quality III“ is aimed at assessing long-term effects of contaminants that aircraft passengers and crew members are exposed to on board.


Press release / 1.12.2022

Designer immune cells for drug discovery, potency and safety testing

Precise therapeutics testing - preventing animal testing.

Press release / 29.6.2022

Project FibroPaths®

Therapeutic modulation of organ fibrosis in biochip format. 

Press release / 28.10.2022

High Performance Center at the COMPAMED 2022

Plasma treatment during 3D printing improves acceptance of implants.

Our research and development expertise

For more than four decades, we have been developing solutions for human health


Cardiopulmonary research

Through the establishment of a Division of Cardiovascular Research in 2021, the long-standing expertise in lung research is experiencing a synergetic further development of high clinical relevance. 

Medical and Pharmaceutical Engineering

Next to innovative inhalation technologies, our focus is on developing novel technologies for administration of therapeutic aerosols by means of smart drug/device combination products.


Malignant disease research

The Fraunhofer ITEM Division of Personalized Tumor Therapy in Regensburg is aimed at understanding a patient’s individual condition, establishing appropriate diagnostics and optimizing therapies.

Bioinformatics and AI

Our researchers develop methods for preparation, analysis and visualization of biomedical data, as well as data models and data analysis pipelines. The focus is on the mapping of cellular and regulatory processes and their translation into applications.



Based on the next generation risk assessment concept, Fraunhofer ITEM develops new assessment strategies to provide predictive models for assessing the safety of compounds, active pharmaceutical ingredients and drugs.


Immunology and infection research

The development, formulation and mode of delivery of anti-infective agents, for example for inhaled administration as drug aerosols, are research topics of current interest at the institute.

Our services


Chemical Safety and Assessment


Translational Biomedical Engineering


Personalized Tumor Therapy


Fraunhofer ITEM

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM

Nikolai-Fuchs-Strasse 1
30625 Hannover

Phone +49 511 5350-0



Models of Lung Disease 2023 - Save the date

On June 22 and 23, 2023, the 21st Fraunhofer Seminar "Models of Lung Disease" will be held in Hannover, Germany. For the 21st time already, this workshop offers experts from academia and industry an excellent platform to discuss the latest topics and questions in lung research. We would be pleased to welcome you at another “summer edition” of this workshop. Please save the date!
Read more


Workshop "Alternatives to Animal Testing" 2023 - Save the date

In 2023, alternative methods to animal testing will again be at the focus of a one-day workshop at Fraunhofer ITEM in Hannover organized by the Fraunhofer Cluster Immune-Mediated Diseases CIMD. Please save the date: June 21, 2023. Apart from expert talks on in-vitro and ex-vivo models for toxicology, pharmacology and infection research, there will be plenty of time for scientific exchange.
Read more


SOT Annual Meeting and ToxExpo 2023 in Nashville

We are excited to be at this year’s SOT Annual Meeting and ToxExpo in Nashville, Tennessee, and will be very happy to share insights into our latest toxicology research with you. Booth number: 1127
Read more


EFSA specialized trainings on certain aspects of food safety risk assessment

This e-learning package will introduce participants to the main principles of different structure-based in-silico approaches for estimation of mainly human health toxicological endpoints. The application of in-silico approaches in ecotoxicology will not be addressed in this course.
Read more

About Fraunhofer ITEM

The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is one of 76 institutes and research institutions of the Fraunhofer-Gesellschaft, the world’s leading applied research organization. Protecting man from health hazards in our industrialized world and contributing to the development of novel therapeutic approaches are the aims Fraunhofer ITEM is pursuing with its contract research. With a focus on cardiopulmonary research, our R&D portfolio includes three business areas: Drug Development, Chemical Safety and Translational Biomedical Engineering. In addition, our scientists in Regensburg do research in the field of personalized tumor therapy.

With a staff of around 450 at its locations in Hannover, Braunschweig and Regensburg, the institute cooperates with industry, service providers, and public authorities in projects that drive economic development and serve the wider benefit of society.


More information about Fraunhofer ITEM