Fraunhofer Institute for Toxicology and Experimental Medicine

Medical research on SARS-CoV-2

With our decades of experience in infection and airway research, drug development, biomedical engineering, and in the field of chemical risk assessment, we are meanwhile involved in numerous projects to fight the COVID-19 pandemic.

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#WeKnowClinical Research

Get some insights into our clinical airway research in our video series #WeKnowClinicalResearch.

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Institute management in tandem

Prof. Dr. Dr. Thomas Thum has joined Fraunhofer ITEM as institute director. He will henceforth manage the institute together with Prof. Dr. Norbert Krug.

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What turns cells into killer cells?

Our Regensburg-based Division of Personalized Tumor Therapy is searching for approaches for novel diagnostics and personalized treatments in the fight against cancer.

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Top-speed antibody development

New fast-track method cuts many months off the time required for process development.

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EU project MDOT

Development of an open-innovation test bed to support small and medium-sized manufacturers of medical devices in the conformity assessment of their products.

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Bioinformatics and Digital Health

Processing large quantities of data is a major challenge of our era, in the life sciences in particular. The Project Group for Bioinformatics has been set up as an “Attract Group” at Fraunhofer ITEM.

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Fighting bacteria with viruses

Fraunhofer scientists have joined forces with partners in the Phage4Cure project to explore alternatives to antibiotics.

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Fraunhofer ITEM: News

News / 19.4.2021

Prof. Thum receives the Paul Martini Prize 2021

Fraunhofer ITEM director honored for his successful research on new treatment options for chronic heart failure.


News / 4.3.2021

Inhibiting cell entry of SARS-CoV-2

In collaboration with DPZ, Fraunhofer ITEM has analyzed the antiviral activity of camostat in human lung tissue.

News / 8.4.2021

iCAIR® has delivered first results

On the way to inhalable drugs against  SARS-CoV-2.


Press release / 1.3.2021

Air purification and disinfection

Fraunhofer IKTS and ITEM have developed a ventilation system, which is able to filter pathogens from ambient air and destroy them in a new process.


Press release / 12.1.2021

Institute management in tandem

Prof. Dr. Dr. Thomas Thum has joined Fraunhofer ITEM as institute director.


Press release / 1.2.2021

Top-speed antibody development

New fast-track method cuts many months off the time required for process development.

News / 4.3.2021

Remobilization of finger joints

Project FingerKIt: Developing for the first time an end-to-end automated process chain for the production of custom-designed implants.

Our services and expertise

Pioneers for sustainable health

Research at Fraunhofer ITEM is focused on human health – and this has been so for almost four decades.

The emphasis is on two aspects: firstly, on protecting health from potentially harmful, in particular airborne substances, be they gases, aerosols, particles, fibers, or nanomaterials, and secondly, on investigating and developing diagnostic and therapeutic approaches, both at the preclinical and clinical levels.

A special focus is on airway research.


Chemical Safety and Assessment


Translational Biomedical Engineering


Personalized Tumor Therapy

Focus of our research

The lung and airways are at the focus of our R&D activities. Furthermore, Fraunhofer ITEM engages in the development and manufacturing of biopharmaceuticals, tumor therapy, and translational biomedical engineering.


Bioinformatics and Digital Health

The Project Group for Bioinformatics improves the analysis of data collected in health research by using novel intelligent methods.


Fraunhofer ITEM

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM

Nikolai-Fuchs-Strasse 1
30625 Hannover

Phone +49 511 5350-0



Training course: In-silico toxicology

This training course will introduce the participants to three different in-silico approaches for estimation of human health toxicological endpoints, namely QSAR models, read-across, and the TTC (threshold of toxicological concern) concept. The application of in-silico approaches in ecotoxicology will not be addressed in this course.
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Virtual SOT

The 2021 Annual Meeting of the Society of Toxicology and ToxExpo will be held as a virtual event. Fraunhofer ITEM scientists will make several contributions to this year’s program.
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OECT Summit 2021

Dr. Philipp Badorrek, Head of Department of Clinical Airway Research at Fraunhofer ITEM, will give a presentation at OECD Summit 2021.
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6th German Pharm-Tox Summit of the German Society for Experimental and Clinical Pharmacology and Toxicology

Dr.-Ing. Katharina Schwarz and Jan Sündermann of Fraunhofer ITEM will each contribute an oral presentation to the program of this year's completely digital 6th German Pharm-Tox Summit.
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About Fraunhofer ITEM

The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is one of 75 institutes and research institutions of the Fraunhofer-Gesellschaft, the world’s leading applied research organization. Protecting man from health hazards in our industrialized world and contributing to the development of novel therapeutic approaches are the aims Fraunhofer ITEM is pursuing with its contract research. With a focus on airway research, our R&D portfolio includes three thematic areas: drug development, chemical safety, and translational biomedical engineering. In addition, our scientists in Regensburg do research in the field of personalized tumor therapy.

With a staff of 394 at its locations in Hannover, Braunschweig and Regensburg, the institute cooperates with industry, service providers, and public authorities in projects that drive economic development and serve the wider benefit of society.

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