Fraunhofer Institute for Toxicology and Experimental Medicine


It is Fraunhofer ITEM's anniversary!

An exciting year 2020

Despite the fight against the pandemic, to which we have contributed with numerous research projects, we have also continued to develop other areas of research. Get an insight into interesting projects performed at Fraunhofer ITEM in 2020, our results, and the people behind all this.

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3D-Druck Kiefer
© Fraunhofer IMTE, Dr. Thomas Friedrich

High-Performance Center

The High-Performance Center Medical and Pharmaceutical Engineering, launched in March, creates a platform for research and the transfer of innovations into patient care.

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Fraunhofer ITEM #weknowhow
© Fraunhofer

Medical research on SARS-CoV-2

With our decades of experience in infection and airway research, drug development, biomedical engineering, and in the field of chemical risk assessment, we are meanwhile involved in numerous projects to fight the COVID-19 pandemic.

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#WeKnowClinical Research

Get some insights into our clinical airway research in our video series #WeKnowClinicalResearch.

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Personalisierte Tumortherapie
© Fraunhofer ITEM, P. Reinig

What turns cells into killer cells?

Our Regensburg-based Division of Personalized Tumor Therapy is searching for approaches for novel diagnostics and personalized treatments in the fight against cancer.

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Vorbereitung für die klinische Prüfung: Zum Herstellungsprozess von Prüfarzneimitteln gehört auch die aseptische Abfüllung der biopharmazeutischen Wirkstoffe wie die der spezifischen Antikörper gegen SARS-CoV-2.
© Fraunhofer ITEM, Ralf Mohr
Vorbereitung für die klinische Prüfung: Zum Herstellungsprozess von Prüfarzneimitteln gehört auch die aseptische Abfüllung der biopharmazeutischen Wirkstoffe wie die der spezifischen Antikörper gegen SARS-CoV-2.

Top-speed antibody development

New fast-track method cuts many months off the time required for process development.

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© Shutterstock, Yurchanka Siarhei
Global network. Blockchain. 3D illustration. Neural networks and artificial intelligence. Abstract technological background with binary code elements; Shutterstock ID 1061069282; Fraunhofer Project Number: 042-154792; Job/Project: EU-Projekt MDOT; Ordering Party: Fraunhofer ITEM

EU project MDOT

Development of an open-innovation test bed to support small and medium-sized manufacturers of medical devices in the conformity assessment of their products.

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© Vasily Smirnov,

Bioinformatics and Digital Health

Processing large quantities of data is a major challenge of our era, in the life sciences in particular. The Project Group for Bioinformatics has been set up as an “Attract Group” at Fraunhofer ITEM.

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Fighting bacteria with viruses

Fraunhofer scientists have joined forces with partners in the Phage4Cure project to explore alternatives to antibiotics.

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Fraunhofer ITEM: News

News / 25.5.2021

Emissions from railway traffic

DZSF project: air pollutant monitoring and dispersion modeling


Press release / 25.5.2021

Chip cytometry

A promising tool for analysis of induced sputum and BAL in multi-center clinical trials

News / 19.5.2021


Contributing to a sustainable future by proactively managing the environmental impact of medicines.


News / 8.4.2021

iCAIR® has delivered first results

On the way to inhalable drugs against  SARS-CoV-2.


Event / 14.6.2021

Science Campus@Home

Stepping stone for female students of STEM subjects for a career in research.


News / 19.4.2021

Prof. Thum receives the Paul Martini Prize 2021

Fraunhofer ITEM director honored for his successful research on new treatment options for chronic heart failure.

News / 27.5.2021

Reviewing OECD Test Guidelines

Fraunhofer IME and ITEM and Ramboll contracted by Umweltbundesamt.

Our services and expertise

Pioneers for sustainable health

Research at Fraunhofer ITEM is focused on human health – and this has been so for almost four decades.

The emphasis is on two aspects: firstly, on protecting health from potentially harmful, in particular airborne substances, be they gases, aerosols, particles, fibers, or nanomaterials, and secondly, on investigating and developing diagnostic and therapeutic approaches, both at the preclinical and clinical levels.

A special focus is on airway research.


Chemical Safety and Assessment


Translational Biomedical Engineering


Personalized Tumor Therapy

Focus of our research

The lung and airways are at the focus of our R&D activities. Furthermore, Fraunhofer ITEM engages in the development and manufacturing of biopharmaceuticals, tumor therapy, and translational biomedical engineering.


Bioinformatics and Digital Health

The Project Group for Bioinformatics improves the analysis of data collected in health research by using novel intelligent methods.


Fraunhofer ITEM

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM

Nikolai-Fuchs-Strasse 1
30625 Hannover

Phone +49 511 5350-0



Training course: In-silico toxicology

This training course will introduce the participants to three different in-silico approaches for estimation of human health toxicological endpoints, namely QSAR models, read-across, and the TTC (threshold of toxicological concern) concept. The application of in-silico approaches in ecotoxicology will not be addressed in this course.
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Science Campus@Home 2021

The virtual event will be held in German. For more information on the agenda and registration, please refer to our German website.
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International Workshop on (Q)SAR in Environmental and Health Sciences 2021

On June 8, 2021, Fraunhofer ITEM scientist Dr. Sylvia Escher will contribute an oral presentation to the program of this year's International Workshop on (Q)SAR in Environmental and Health Sciences in the session "Development, evaluation and application of QSARs and Thresholds of Toxicological Concern (TTC)".
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DGP Congress 2021

From June 2 to 5, the scientific annual congress of the German Respiratory Society (DGP) will be held as the central forum for respiratory medicine in the German-speaking area. The program includes numerous contributions from Fraunhofer ITEM – from Prof. Antje Prasse as chair of the DGP program committee, Prof. Jens Hohlfeld, Dr. Meike Müller, Saskia Carstensen, and Dr. Benedikt Jäger.
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About Fraunhofer ITEM

The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is one of 75 institutes and research institutions of the Fraunhofer-Gesellschaft, the world’s leading applied research organization. Protecting man from health hazards in our industrialized world and contributing to the development of novel therapeutic approaches are the aims Fraunhofer ITEM is pursuing with its contract research. With a focus on airway research, our R&D portfolio includes three thematic areas: drug development, chemical safety, and translational biomedical engineering. In addition, our scientists in Regensburg do research in the field of personalized tumor therapy.

With a staff of 394 at its locations in Hannover, Braunschweig and Regensburg, the institute cooperates with industry, service providers, and public authorities in projects that drive economic development and serve the wider benefit of society.

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