Fraunhofer Institute for Toxicology and Experimental Medicine

Institute management in tandem

Prof. Dr. Dr. Thomas Thum has joined Fraunhofer ITEM as institute director. He will henceforth manage the institute together with Prof. Dr. Norbert Krug.

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Models of Lung Disease 2021: registration open!

The next Fraunhofer Seminar “Models of Lung Disease” will be held on January 21 and 22, 2021. The focus of this virtual conference will be on different aspects of SARS-CoV-2.

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What turns cells into killer cells?

Our Regensburg-based Division of Personalized Tumor Therapy is searching for approaches for novel diagnostics and personalized treatments in the fight against cancer.

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Accelerated production of a passive vaccine against COVID-19

Fraunhofer ITEM and Corat Therapeutics GmbH are beginning production of a specific SARS-CoV-2 antibody.

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Medical research on SARS-CoV-2

With our decades of experience in infection and airway research, drug development, biomedical engineering, and in the field of chemical risk assessment, we are meanwhile involved in numerous projects to fight the COVID-19 pandemic.

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EU project MDOT

Development of an open-innovation test bed to support small and medium-sized manufacturers of medical devices in the conformity assessment of their products.

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Bioinformatics and Digital Health

Processing large quantities of data is a major challenge of our era, in the life sciences in particular. The Project Group for Bioinformatics has been set up as an “Attract Group” at Fraunhofer ITEM.

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Fighting bacteria with viruses

Fraunhofer scientists have joined forces with partners in the Phage4Cure project to explore alternatives to antibiotics.

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Replacing animal testing

Fraunhofer ITEM advances the development of new-approach methodologies. Our scientists Dr. Sylvia Escher and Dr. Tanja Hansen discussed the paradigm shift in chemical risk assessment.

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Fraunhofer ITEM: News


News / 15.1.2021

Models of Lung Disease: registration still open!

Virtual conference on January 21 and 22, this year with a focus on different aspects of SARS-CoV-2. Register now!

News / 18.11.2020

Human antibody against COVID-19 ready for clinical trials


Press release / 4.1.2021

Avoiding animal experimentation

Toxicological risk assessment for chemicals

News / 19.11.2020

Publication in Sensors

"Laser-facilitated additive manufacturing enables fabrication of biocompatible neural devices"

Press release / 12.1.2021

Institute management in tandem

Prof. Dr. Dr. Thomas Thum has joined Fraunhofer ITEM as institute director. He will henceforth manage the institute together with Prof. Dr. Norbert Krug.

News / 16.12.2020

Discovery of novel COVID-19 therapeutics

Development of a drug screening pipeline

Our services and expertise

Pioneers for sustainable health

Research at Fraunhofer ITEM is focused on human health – and this has been so for almost four decades.

The emphasis is on two aspects: firstly, on protecting health from potentially harmful, in particular airborne substances, be they gases, aerosols, particles, fibers, or nanomaterials, and secondly, on investigating and developing diagnostic and therapeutic approaches, both at the preclinical and clinical levels.

A special focus is on airway research.


Chemical Safety and Assessment


Translational Biomedical Engineering


Personalized Tumor Therapy

Focus of our research

The lung and airways are at the focus of our R&D activities. Furthermore, Fraunhofer ITEM engages in the development and manufacturing of biopharmaceuticals, tumor therapy, and translational biomedical engineering.


Bioinformatics and Digital Health

The Project Group for Bioinformatics improves the analysis of data collected in health research by using novel intelligent methods.


Fraunhofer ITEM

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM

Nikolai-Fuchs-Strasse 1
30625 Hannover

Phone +49 511 5350-0



EFSA training no. 4: Principles of genotoxicity in scientific assessment

This online training course will give guidance to participants on how to evaluate study data on genotoxicity and how to integrate corresponding testing results in risk assessment.
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The Festival of Genomics & Biodata 2021

Bernhard Polzer, Manager of the Fraunhofer ITEM Working Group on Cellular and Molecular Diagnostics, will present research work on the application of single-cell analysis in CSF to neurological tumors.
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EFSA training no. 6: Computational toxicology tools

This online training course will introduce participants to three different in-silico approaches, namely QSAR models, read-across, and the TTC (threshold of toxicological concern) concept, including demonstrations and explanations of currently available predictive toxicology models.
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Models of Lung Disease 2021

A special edition of the Fraunhofer Seminar "Models of Lung Disease" will be held on January 21 and 22, 2021 – as a virtual conference with a focus on the new coronavirus SARS-CoV-2.
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About Fraunhofer ITEM

The Fraunhofer Institute for Toxicology and Experimental Medicine ITEM is one of 74 institutions of the Fraunhofer-Gesellschaft, Europe's leading organization for applied research. Protecting man from health hazards in our industrialized world and contributing to the development of novel therapeutic approaches are the aims Fraunhofer ITEM is pursuing with its contract research. With a focus on airway research, our R&D portfolio includes three thematic areas: drug development, chemical safety, and translational biomedical engineering. In addition, our scientists in Regensburg do research in the field of personalized tumor therapy.

With a staff of 357 at its locations in Hannover, Braunschweig and Regensburg, the institute cooperates with industry, service providers, and public authorities in projects that drive economic development and serve the wider benefit of society.

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