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The National Institute for Public Health and the Environment (RIVM) provides an e-learning package on benchmark dose (BMD) modeling. The package comprises three e-learning modules, followed by a webinar. Trainees are expected to study and complete the e-learning modules on their own prior to the concluding webinar. Each module will consist of a 20-minute lecture, followed by a quiz.

This e-learning package will give guidance to participants on how to evaluate study data on genotoxicity and how to integrate corresponding testing results in risk assessment. Although genotoxicity testing of compounds used intentionally in food and feed or being natural and environmental contaminants has been routine for many years, the strategies/recommended testing batteries have changed over time.

The Fraunhofer Cluster of Excellence Immune-Mediated Diseases CIMD aims to facilitate and simplify education along the 4Ds (Drugs, Diagnostics, Data, Devices) by supporting young scientists. Cooperation between different disciplines is to be encouraged - a prerequisite for the implementation of 4Ds. In addition to various workshops along the 4Ds, the cluster is planning a winter school in Leipzig, which is aimed primarily at doctoral students, young postdocs and project collaborators of the Fraunhofer CIMD.

This training course will introduce the participants to three different in-silico approaches for estimation of human health toxicological endpoints, namely QSAR models, read-across, and the TTC (threshold of toxicological concern) concept. The application of in-silico approaches in ecotoxicology will not be addressed in this course.

On "Day of Immune Research“ current topics in the field of immune-mediated diseases will be presented and discussed across disciplines and across institute borders. Current challenges are to be discussed and new solutions shall be jointly developed.