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Institute Expand / Hide

• Organizational structure

• Institute director

• Quality assurance

• Our network

• Institute chronicles

• Board of trustees

• Mission statement

• Departments and contact names

Services and Expertise Expand / Hide

• Drug Development Expand / Hide

  • GMP manufacturing of biopharmaceuticals for clinical trials

  • Regulatory research and risk assessment in drug development

  • Preclinical research and testing Expand / Hide

    • Efficacy

    • Toxicology testing

  • Clinical trials

• Chemical safety and assessment Expand / Hide

  • Method development and customized analyses

  • Toxicology testing

  • Exposure characterization

  • Regulatory research and risk assessment

• Translational Biomedical Engineering Expand / Hide

  • Device development and manufacturing processes

  • Testing and test methods

  • Regulatory support

• Personalized Tumor Therapy Expand / Hide

  • Single-cell analytics Expand / Hide

    • Enrichment, isolation and molecular analysis of rare cells

    • Decoding single cells

  • Innovative tumor models Expand / Hide

    • In-vitro and in-vivo drug testing

    • Advanced preclinical PDX models

  • Mathematical modeling and bioinformatics Expand / Hide

    • Multi-level disease modeling

    • Bioinformatics services and consulting

Focuses of Research Expand / Hide

• Drug Development Expand / Hide

  • Testing of cell-based medicinal products

  • Controlling antibiotic-resistant pathogens

  • Human lung tissue for research on respiratory diseases

  • Non-invasive breath gas analysis

  • Development of novel biomarkers for use in clinical trials

  • Clinical and translational fibrosis research

  • Imaging of the human lung - visualizing drug efficacy

• Chemical Safety and Assessment Expand / Hide

  • Exposure science

  • Toxicity of fibers, particles, and nanomaterials

  • Analysis of indoor and workplace air quality

  • Replacing animal testing

• Translational Biomedical Engineering Expand / Hide

  • Innovative approaches for inhaled aerosol therapies

  • Medical and environmental sensors

  • Accelerated life cycle testing

• Personalized Tumor Therapy Expand / Hide

  • Single-cell technologies

  • Identification of target structures and therapy prediction

  • Mathematical modeling of disease processes

  • Models of treatment and metastasis formation

CRC Hannover

Lighthouse projects Expand / Hide

• High-Performance Center Translational Biomedical Engineering

• German-Australian iCAIR project

• "Phage4Cure": bacteriophages as an approved drug

• EU-ToxRisk: toxicological risk assessment

• Cluster of Excellence for Immune-Mediated Diseases CIMD

Press and media Expand / Hide

• Newsletter

• Annual reports

• Publications

• Press releases Expand / Hide

  • PM CPA Takeda

  • PM Bereich Personalisierte Tumortherapie

  • PM Nature Papers

  • Change in management 2017

  • Center Inauguration

  • New EU regulation on medical devices

  • eTRANSAFE – collaborative research project aimed at improving safety in the drug development process

  • iCAIR

  • Initiative Wissenschaft

  • Phage4Cure

  • German-Australian project iCAIR

  • Proof-of-Concept-Initiative

  • Fraunhofer researcher Prof. Christoph Klein received the “Fidler Innovation Award”

  • Science Campus 2018

  • InnoHealth Australia 2017-2019

  • Medical Device Regulation

  • Synergy Boost

  • InnoHealth Australia 2017-2019

  • Gentle treatment for premature babies with lung diseases

  • Open-innovation test bed for medical devices

  • Press Release iCAIR

  • EU-project MDOT

• News Expand / Hide

  • Fraunhofer ITEM scientists won prizes at the 5th DZL Annual Meeting

  • Poster prize to Fraunhofer ITEM scientist

  • Our Project Group on Personalized Tumor Therapy is now ISO 9001 certified

  • Testing of a novel anti-inflammatory drug for treating COPD based on endotoxin challenge

  • Poster prize to Fraunhofer ITEM scientist

• Thematic Flyers

Events Expand / Hide

• Looking back at “Models of Lung Disease” 2018

Career Expand / Hide

• Professionals

• Postgraduates

• Undergraduates

• Working at Fraunhofer

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