We are very excited to be back on site this year at the SOT Annual Meeting and ToxExpo in San Diego, California (USA), March 27-31, 2022, to give diverse insights into our toxicology research.
Booth number: 1328
Tuesday, March 29, 2022, 3:50-4:10 p.m., Ballroom 6E
Presenting author: Sylvia Escher
2017: "Influence of extremely low-frequency magnetic fields on the development of childhood leukemia: An experimental study in a susceptible mouse model”
Monday, March 28, 2022, 4:00-4:15 p.m., CC Room 8
Presenting author: Dmitrij Sachno
Fraunhofer vs. Corona: Drug Repurposing Using the Example of Inhalation Therapy Against Covid-19
Monday, March 28, 2022, 9:00-10:00 a.m., CC Room 22
New drugs against Covid-19 are urgently needed. Repurposing of existing drugs enables faster development and minimizes risks. Inhalable drugs offer the benefits of non-invasive administration and less systemic side effects. Within the DRECOR project, we selected and identified drug repurposing candidates using in-vitro/in-vivo inhalation studies and PK/Tox assessments.
PBPK Modeling: The Road to Systemic Toxicity from External to Internal Exposure
Tuesday, March 29, 2022, 9:00-10:00 a.m., CC Room 22
Physiologically-based pharmacokinetic (PBPK) models intrinsically link external and internal exposure, dose response, and target organ toxicity. Integration of innovative in vitro test systems and knowledge on in vivo physiological parameters are crucial for an integrated approach to testing and assessment (IATA). Our PBPK model specifically addresses the complex dosimetry for inhalation toxicity.
Indoor Air Quality and Human Exposure
Wednesday, March 30, 2022, 9:00-10:00 a.m., CC Room 22
Nowadays, people spend most of their lives indoors – at work, home, schools, or traveling. Indoor air pollution has become an increasingly important issue, with one focus on ventilation and filter systems. Fraunhofer ITEM combines expertise in inhalation toxicology with chemical analyses and human exposure for selected scenarios.
San Diego
San Diego Convention Center
111 West Harbor Drive
San Diego, CA 92101, USA
March 27, 2022 - March 31, 2022
English
3710: Poster board P370: Transcriptome data to substantiate the assessment of similar mechanisms of action in a read-across context
Tuesday, March 29, 2022, 9:00-10:45 a.m.
Presenting author: Christina Drake
Session Title: Bioinformatics
4317: Poster board P269: Zet-O-Map: Identify principal molecular drivers of (dys)morphogenesis in zebrafish
Wednesday, March 30, 2022, 9:00-10:45 a.m.
Presenting author: Matthias Wehr
Session title: Reproductive and Developmental Toxicology III
4050: Poster board P749: Development and application of a physiologically based kinetic (PBK) model for the inhalation route
Tuesday, March 29, 2022, 10:45 a.m. – 12:30 p.m.
Presenting author: Norman Nowak
Session title: Biological Modeling
4202: Poster board P132: Organic solvents alter gene expression pattern in human precision-cut liver slices
Wednesday, March 30, 2022, 9:00-10:45 a.m.
Presenting author: Leroy Elenschneider
Session title: Alternatives to Mammalian Models II
3658: Poster board P305: Toxicokinetic study following intratracheal instillation or oral gavage of two Be-7 tagged carbon black samples
Tuesday, March 29, 2022, 2:30-4:15 p.m.
Presenting author: Otto Creutzenberg
Session title: Nanotoxicology: In Vivo
4694: Poster board P746: Influence of the H1 antihistamine mepyramine on the antibacterial effect of florfenicol in pigs
Wednesday, March 30, 2022, 2:30-4:15 p.m.
Presenting author: Gustav Bruer
Session title: Systems Biology
Fraunhofer Institute for Toxicology and Experimental Medicine