Wir freuen uns sehr, dieses Jahr vom 27. bis 31. März 2022 beim SOT-Jahreskongress und der ToxExpo in San Diego (Kalifornien, USA) wieder vor Ort dabei zu sein, um vielfältige Einblicke in unsere toxikologische Forschung zu geben.
Standnummer: 1328
1167: »Next-generation human risk assessment toward regulatory acceptance using read-across case studies«
Dienstag, 29. März 2022, 15.50-16.10 Uhr, Ballroom 6E
Vortragende: Sylvia Escher
2017: »Influence of extremely low-frequency magnetic fields on the development of childhood leukemia: An experimental study in a susceptible mouse model«
Montag, 28. März 2022, 16.00-16.15 Uhr, CC Raum 8
Vortragender: Dmitrij Sachno
Fraunhofer vs. Corona: Drug Repurposing Using the Example of Inhalation Therapy Against Covid-19
Montag, 28. März 2022, 9.00-10.00 Uhr, CC Raum 22
New drugs against Covid-19 are urgently needed. Repurposing of existing drugs enables faster development and minimizes risks. Inhalable drugs offer the benefits of non-invasive administration and less systemic side effects. Within the DRECOR project, we selected and identified drug repurposing candidates using in-vitro/in-vivo inhalation studies and PK/Tox assessments.
PBPK Modeling: The Road to Systemic Toxicity from External to Internal Exposure
Dienstag, 29. März 2022, 9.00-10.00 Uhr, CC Raum 22
Physiologically-based pharmacokinetic (PBPK) models intrinsically link external and internal exposure, dose response, and target organ toxicity. Integration of innovative in vitro test systems and knowledge on in vivo physiological parameters are crucial for an integrated approach to testing and assessment (IATA). Our PBPK model specifically addresses the complex dosimetry for inhalation toxicity.
Indoor Air Quality and Human Exposure
Mittwoch, 30. März 2022, 9.00-10.00 Uhr, CC Raum 22
Nowadays, people spend most of their lives indoors – at work, home, schools, or traveling. Indoor air pollution has become an increasingly important issue, with one focus on ventilation and filter systems. Fraunhofer ITEM combines expertise in inhalation toxicology with chemical analyses and human exposure for selected scenarios.
San Diego
San Diego Convention Center
111 West Harbor Drive
San Diego, CA 92101, USA
27. März 2022 - 31. März 2022
Englisch
3710: Poster-Board P370: Transcriptome data to substantiate the assessment of similar mechanisms of action in a read-across context
Dienstag, 29. März 2022, 9.00-10.45 Uhr
Autorin: Christina Drake
Session-Titel: Bioinformatics
4317: Poster-Board P269: Zet-O-Map: Identify principal molecular drivers of (dys)morphogenesis in zebrafish
Mittwoch, 30. März 2022, 9.00-10.45 Uhr
Autor: Matthias Wehr
Session-Titel: Reproductive and Developmental Toxicology III
4050: Poster-Board P749: Development and application of a physiologically based kinetic (PBK) model for the inhalation route
Dienstag, 29. März 2022,10.45-12.30 Uhr
Autor: Norman Nowak
Session-Titel: Biological Modeling
4202: Poster-Board P132: Organic solvents alter gene expression pattern in human precision-cut liver slices
Mittwoch, 30. März 2022, 9.00-10.45 Uhr
Autor: Leroy Elenschneider
Session-Titel: Alternatives to Mammalian Models II
3658: Poster-Board P305: Toxicokinetic study following intratracheal instillation or oral gavage of two Be-7 tagged carbon black samples
Dienstag, 29. März 2022,14.30-16.15 Uhr
Autor: Otto Creutzenberg
Session-Titel: Nanotoxicology: In Vivo
4694: Poster-Board P746: Influence of the H1 antihistamine mepyramine on the antibacterial effect of florfenicol in pigs
Mittwoch, 30. März 2022,14.30-16.15 Uhr
Autor: Gustav Bruer
Session-Titel: Systems Biology
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin