Fraunhofer Institute for Toxicology and Experimental Medicine09:15 |
Welcome Institute Director Prof. Dr. Dr. T. Thum, Fraunhofer ITEM |
Session 1: Advanced in vitro and ex vivo systems in (auto)immune diseases Chair: Dr. K. Sewald, Fraunhofer ITEM |
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09:30 |
iPSC, organoids, organotypic models and PCS as novel tools to study tissue responses in autoimmune diseases Prof. Dr. J. Distler, University of Düsseldorf, Düsseldorf (Germany) |
10:00 |
Functional characterization of innate and adaptive immune responses in intestinal tissue slices from IBD vs. non-IBD patients ex-vivo K. Grieger and V. Beneke, Fraunhofer ITEM |
10:30 |
Zebrafish embryo as a testsystem: AOP development and use for immunotoxicity assessment Dr. S. Eilebrecht, Fraunhofer IME, Schmallenberg |
11:00 |
Coffee break |
Session 2: Opportunities and challenges for integrating new methodologies in the toxicological evaluation and biomarker research (including industry perspectives) Chair: Dr. A. Bitsch, Fraunhofer ITEM |
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11:30 |
Using lung organoids to dissect environmentally induced cell circuit perturbations Dr. C. Voss, Helmholtz Center Munich, Munich (Germany) |
12:00 |
Use of metabolomics for biomarker identification: standardization of analysis and new chances with NMR metabolomics Dr. S. Schuchardt and Dr. K. Blümlein, Fraunhofer ITEM |
12:30 |
Metabolomics and its use in safety science of chemicals Prof. Dr. H. Kamp, BASF Metabolome Solutions GmbH, Berlin (Germany) |
13:00 |
Lunch break & poster session |
14:30 |
Defined approaches for skin sensitization – an industry view Dr. P. Benndorf, Henkel, Düsseldorf (Germany) |
Session 3: Alternatives to animal testing in infection research Chair: Dr. F. Dahlmann, Fraunhofer ITEM |
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15:00 |
The hITM - a modern in vitro platform for human-specific infection research Dr. D. Zdzieblo, Fraunhofer ISC, Würzburg (Germany) |
15:30 |
Coffee break |
16:00 |
Dissecting host-pathogen interaction in organ-on-chip models Prof. Dr. A. Mosig, University of Jena, Jena (Germany) |
16:30 |
Alternatives to animal testing models that mimic hypoxia during infection and inflammation Prof. Dr. M. Köckritz-Blickwede, University of Veterinary Medicine, Hannover (Germany) |
17:00 |
Differentiated Human Airway Epithelial Cell model in virology and antiviral drug discovery Dr. P. Guillon, Griffith University, Gold Coast (Australia) |
17:30 |
End |
18:00 |
Guided tours to different non-clinical and clinical departments of Fraunhofer ITEM:
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Workshop »Alternatives to Animal Testing«
June 21, 2023 | Hannover
© Fraunhofer ITEM, Ralf Mohr
Program
Wednesday, June 21, 2023 (as of June 5, 2023, subject to change without notice):