11:45 |
Welcome Norbert Krug and Christian Bär, Fraunhofer ITEM, Hannover (Germany) |
Session 1: Target discovery and lead optimization Chair: Lena Wiese, Fraunhofer ITEM / GU Frankfurt, Hannover/Frankfurt (Germany) |
12:00 |
Investigating early mechanisms and potential targets in virus-induced COPD exacerbations through in silico modeling Mats Jirstrand and Mikael Wallman, Fraunhofer Chalmers, Göteborg (Sweden) |
12:20 |
Integrative bioinformatics analysis of RNA targets in immune-mediated diseases Meik Kunz, Fraunhofer ITEM / FAU Erlangen, Hannover/Erlangen (Germany) |
12:40 |
tba. |
Session 2: Advanced human preclinical models Chair: Katherina Sewald, Fraunhofer ITEM (Germany) |
13:00 |
Targeting immune cells to facilitate the development of novel therapies Nico Lachmann, Fraunhofer ITEM / Hannover Medical School, Hannover (Germany) |
13:20 |
The development of in vitro skin models: From simple epidermis to complex hiPSC-derived organoids models Dieter Groneberg, Fraunhofer ISC - TLZ-RT, Würzburg (Germany) |
13:40 |
Multi-cellular human cardiac organoids, a versatile platform for modelling cardiovascular disease Elisa Mohr, Hannover Medical School, Hannover (Germany) |
14:00 |
Poster viewing (I) |
Special Session (I): Innovations towards clinical application Chair: Christian Bär, Fraunhofer ITEM / Hannover Medical School, Hannover (Germany) |
14:30 |
RNAuto – automated production technologies of mRNA-based vaccines and cell therapies Sandy Tretbar, Fraunhofer IZI, Leipzig (Germany) |
14:50 |
Translational development of inhaled antiviral RNAi fighting parainfluenza infection Armin Braun, Fraunhofer ITEM, Hannover (Germany) |
15:10 |
Advancing respiratory delivery utilizing new inhaler technologies Gerhard Pohlmann, Fraunhofer ITEM, Hannover (Germany) |
Session 3: Targeted delivery strategies Chair: Jan Fiedler, Fraunhofer ITEM, Hannover (Germany) |
15:30 |
Glycobiotechnology as a tool for drug delivery Sophia Rosencrantz, Fraunhofer IAP, Potsdam (Germany) |
15:50 |
Particle-based solutions for RNA encapsulation Sofia Dembski, Fraunhofer ISC - TLZ-RT, Würzburg (Germany) |
16:10 |
Polymeric PEI/PPI-based nanoparticles as non-viral platform technology for RNA delivery in vivo and ex vivo Achim Aigner, Leipzig University, Leipzig (Germany) |
16:30 |
Optimizing the properties of lipid nanoparticles through advanced manufacturing technologies Christoph Hein, Fraunhofer IPK, Berlin (Germany) |
16:50 |
Poster viewing (II) |
Session 4: RNA clinical development Chair: Norbert Krug, Fraunhofer ITEM, Hannover (Germany) |
17:20 |
Clinical development & regulatory affairs for RNA therapies Philipp Badorrek, Fraunhofer ITEM, Hannover (Germany) |
17:40 |
Survey lecture: miRNA therapies on their way towards clinical application Christian Bär, Fraunhofer ITEM / Hannover Medical School, Hannover (Germany) |
Special Session (II): Industry perspective Chair: Ruben Rosencrantz, Fraunhofer IAP, Potsdam (Germany) |
18:00-19:00 |
Speakers from CureVac, Evonik, and TRON gGmbH |
Evening session |
19:00 |
Poster viewing with fingerfood reception |
19:55 |
Poster award ceremony |
20:00 |
End |
Fraunhofer Institute for Toxicology and Experimental Medicine
