8:45 |
Welcome Armin Braun, Fraunhofer ITEM (Germany) |
Session 1: Human immune competent models of lung disease Chairs: Armin Braun / Katherina Sewald, Fraunhofer ITEM (Germany) |
9:00 |
Alveolar organoids with innate and adaptive immunity Linda Steinacher, Roche (Switzerland) |
9:30 |
Functional single cell perturbations in lung tissue slice cultures – understanding chronic lung disease one cell at a time Lena Cords, Helmholtz Munich (Germany) |
10:00 |
The use of human precision cut lung slices for preclinical drug development for airway diseases Katherina Sewald, Fraunhofer ITEM (Germany) |
10:30 |
Coffee |
11:00 |
The clock is ticking: models of lung aging Mareike Lehmann, Philipps University Marburg (Germany) |
11:30 |
Formulation of RNA-loaded lipid nanoparticles as inhalable dry powder Benjamin Winkeljahn, RnHale (Germany) |
12:00 |
Enhancing CRISPR/Cas9 gene editing in lung tumor cells: optimization of lipid nanoparticles for potential inhalation therapy Simone Carneiro, Ludwig-Maximilians-University Munich (Germany) |
12:30 |
Lunch |
Session 2: RNA-based technologies in research and drug development Chair: Philippe Vollmer Barbosa, Fraunhofer ITEM (Germany) |
13:30 |
Targeted RNA drug delivery – possible new treatment options for severe lung diseases Thomas Frischmuth, RNAtics (Germany) |
14:00 |
mRNA therapy for asthma Christian Plank, Ethris (Germany) |
14:30 |
Coffee |
Session 3: SPRIND: A quantum shift for new antiviral agents - the winning teams Chair: Franziska Dahlmann, Fraunhofer ITEM (Germany) |
15:00 |
Innovative inhalable RNA to fight viral threats Hasan Issa, AVOCET (Germany) |
15:20 |
iGUARD – next-generation siRNA inhalation therapy for respiratory diseases Philippe Vollmer Barbosa, Fraunhofer ITEM (Germany) |
15:40 |
Engineered lectins as bifunctional tools for enhanced virus retention in mucus: towards novel broad-spectrum antivirals against flu Seray Sahsuvar, Free University Berlin (Germany) |
16:00 Poster session - snacks and drinks |
Session 4: New anti-infective strategies Chair: Thomas Tschernig, University of Saarland (Germany) |
17:00 |
Harnessing nanobody superpowers against the respiratory virus human metapneumovirus Patrice Guillon, Griffith University (Australia) |
17:30 |
Structure-guided anti-parainfluenza drug candidate discovery; from in silico to in vivo Mark von Itzstein, Griffith University (Australia) |
18:00 |
Guided tours to different non-clinical and clinical departments of Fraunhofer ITEM, e. g.:
- PCLS
- Lung function and IPL
- In-vitro inhalation
- Biomedical engineering
- CRC Hannover
|
18:30 |
Award to the best posters |
18:45 |
Dinner |
21:30 |
Summary and conclusion day 1 Armin Braun, Fraunhofer ITEM (Germany) |