Publications of Fraunhofer ITEM

Baric, V., Grossmann, H. K., Koch, W., Mädler, L. (2018).
Quantitative characterization of mixing in multicomponent nanoparticle aggregates.
Particle & Particle Systems Characterization [Epub ahead of print]. doi: 10.1002/ppsc.201800177
https://onlinelibrary.wiley.com/doi/abs/10.1002/ppsc.201800177

Behrens, A., Foremny, K., Doll, T. (2018).
Carbon nanotube-silicone rubber on active thin-film implants.
Physica Status Solidi a-Applications and Materials Science 215(15). doi: 10.1002/pssa.201700873
https://onlinelibrary.wiley.com/doi/abs/10.1002/pssa.201700873

Brändli-Baiocco, A., Balme, E., Bruder, M., Chandra, S., Hellmann, J., Hoenerhoff, M. J., Kambara, T., Landes, C., Lenz, B., Mense, M., Rittinghausen, S., Satoh, H., Schorsch, F., Seeliger, F., Tanaka, T., Tsuchitani, M., Wojcinski, Z., Rosol, T. J. (2018).
Nonproliferative and proliferative lesions of the rat and mouse endocrine system.
Journal of Toxicologic Pathology. 31(3 Suppl): 1S-95S. doi: 10.1293/tox.31.1S
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108091/

Dunkhorst, W., Lipowicz, P., Li, W., Hux, C., Wang, Q., Koch, W. (2018).
In-situ characterization of e-cigarette aerosols by 90°-light scattering of polarized light.
Aerosol Science and Technology 52(7): 717-724. doi: 10.1080/02786826.2018.1464646
https://www.tandfonline.com/doi/abs/10.1080/02786826.2018.1464646

Emma, R., Bansal, A. T., Kolmert, J., Wheelock, C. E., Dahlen, S. E., Loza, M. J., De Meulder, B., Lefaudeux, D., Auffray, C., Dahlen, B., Bakke, P. S., Chanez, P., Fowler, S. J., Horvath, I., Montuschi, P., Krug, N., Sanak, M., Sandstrom, T., Shaw, D. E., Fleming, L. J., Djukanovic, R., Howarth, P. H., Singer, F., Sousa, A. R., Sterk, P. J., Corfield, J., Pandis, I., Chung, K. F., Adcock, I. M., Lutter, R., Fabbella, L., Caruso, M., Group, U. B. S. (2018).
Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort. 
PloS One 13(9): e0203874. doi: 10.1371/journal.pone.0203874
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0203874 - Open Access

Hekking, P. P., Loza, M. J., Pavlidis, S., de Meulder, B., Lefaudeux, D., Baribaud, F., Auffray, C., Wagener, A. H., Brinkman, P. I., Lutter, R. I., Bansal, A. T., Sousa, A. R., Bates, S. A., Pandis, Y., Fleming, L. J., Shaw, D. E., Fowler, S. J., Guo, Y., Meiser, A., Sun, K., Corfield, J., Howarth, P. H., Bel, E. H., Adcock, I. M., Chung, K. F., Djukanovic, R., Sterk, P. J., Group, U. B. S. (2018).
Pathway discovery using transcriptomic profiles in adult-onset severe asthma.
Journal of Allergy and Clinical Immunology 141(4): 1280-1290. doi: 10.1016/j.jaci.2017.06.037
https://www.sciencedirect.com/science/article/pii/S0091674917311958?via%3Dihub

Hesse, S., Hahn, S., Lamb, L., Basinas, I., Apsley, A., van Tongeren, M. (2018). 
Review of Tier 1 workplace exposure estimates for petroleum substances in REACH dossiers. Brussels, Concawe. 131 p. https://www.concawe.eu/wp-content/uploads/Rpt_18-13.pdf

Kern, A. L., Gutberlet, M., Qing, K., Voskrebenzev, A., Klimes, F., Kaireit, T. F., Czerner, C., Biller, H., Wacker, F., Ruppert, K., Hohlfeld, J. M., Vogel-Claussen, J. (2018).
Regional investigation of lung function and microstructure parameters by localized (129) Xe chemical shift saturation recovery and dissolved-phase imaging: A reproducibility study. 
Magnetic Resonance in Medicine [Epub ahead of print]. doi: 10.1002/mrm.27407 https://onlinelibrary.wiley.com/doi/abs/10.1002/mrm.27407

Kilias, A., Canales, A., Froriep, U. P., Park, S., Egert, U., Anikeeva, P. (2018).
Optogenetic entrainment of neural oscillations with hybrid fiber probes. Journal of Neural Engineering 15(5): 056006. doi: 10.1088/1741-2552/aacdb9 http://iopscience.iop.org/article/10.1088/1741-2552/aacdb9/meta

Lapp, S., Bube, A., Colbatzky, F. A., Ernst, H., Kellner, R., Nolte, T., Rinke, M. (2018). Best practice approach for assessment of microchip-associated tumors in preclinical safety studies: position of the Registry of Industrial Toxicology Animal-data (RITA). 
Toxicologic Pathology [Epub ahead of print]: 7 p. doi: 10.1177/0192623318792541 http://journals.sagepub.com/doi/10.1177/0192623318792541

Okmen, B., Mathow, D., Hof, A., Lahrmann, U., Assmann, D., Doehlemann, G. (2018).
Mining the effector repertoire of the biotrophic fungal pathogen Ustilago hordei during host and non-host infection. Mol Plant Pathol [Epub ahead of print]. doi: 10.1111/mpp.12732 https://onlinelibrary.wiley.com/doi/abs/10.1111/mpp.12732

Prasse, A., Binder, H., Schupp, J. C., Kayser, G., Bargagli, E., Jaeger, B., Hess, M., Rittinghausen, S., Vuga, L., Lynn, H., Violette, S., Jung, B., Quast, K., Vanaudenaerde, B., Xu, Y., Hohlfeld, J. M., Krug, N., Herazo-Maya, J. D., Rottoli, P., Wuyts, W. A., Kaminski, N. (2018). BAL cell gene expression is indicative of outcome and airway basal cell involvement in IPF. American Journal of Respiratory and Critical Care Medicine [Epub ahead of print]. doi: 10.1164/rccm.201712-2551OC https://www.atsjournals.org/doi/10.1164/rccm.201712-2551OC

Ramos, M. F., Baker, J., Atzpodien, E. A., Bach, U., Brassard, J., Cartwright, J., Farman, C., Fishman, C., Jacobsen, M., Junker-Walker, U., Kuper, F., Moreno, M. C. R., Rittinghausen, S., Schafer, K., Tanaka, K., Teixeira, L., Yoshizawa, K., Zhang, H. (2018).
Nonproliferative and proliferative lesions of the ratand mouse special sense organs(ocular [eye and glands], olfactory and otic).
Journal of Toxicologic Pathology 31(3 Suppl): 97S-214S. doi: 10.1293/tox.31.97S
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108092/

Siebers, K., Fink, B., Zakrzewicz, A., Agné, A., Richter, K., Konzok, S., Hecker, A., Zukunft, S., Küllmar, M., Klein, J., McIntosh, J. M., Timm, T., Sewald, K., Padberg, W., Aggarwal, N., Chamulitrat, W., Santoso, S., Xia, W., Janciauskiene, S., Grau, V. (2018).
Alpha-1 antitrypsin inhibits ATP-mediated release of interleukin-1beta via CD36 and nicotinic acetylcholine receptors.
Frontiers in Immunology 9: 877. doi: 10.3389/fimmu.2018.00877
https://www.frontiersin.org/articles/10.3389/fimmu.2018.00877/full - Open Access

Zmora, P., Hoffmann, M., Kollmus, H., Moldenhauer, A. S., Danov, O., Braun, A., Winkler, M., Schughart, K., Pohlmann, S. (2018).
TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1.
Journal of Biological Chemistry 293(36): 13863-13873. doi: 10.1074/jbc.RA118.001273
http://www.jbc.org/content/293/36/13863.abstract

Bernstein, D. M., Toth, B., Rogers, R. A., Sepulveda, R., Kunzendorf, P., Phillips, J. I., Ernst, H. (2018).
Evaluation of the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to chrysotile or crocidolite asbestos in a 28-day quantitative inhalation toxicology study.
Toxicology and Applied Pharmacology 351: 74-92.
doi: 10.1016/j.taap.2018.04.033
https://www.sciencedirect.com/science/article/pii/S0041008X18301777?via%3Dihub

Burg, D., Schofield, J. P. R., Brandsma, J., Staykova, D., Folisi, C., Bansal, A., Nicholas, B., Xian, Y., Rowe, A., Corfield, J., Wilson, S., Ward, J., Lutter, R., Fleming, L., Shaw, D. E., Bakke, P. S., Caruso, M., Dahlen, S. E., Fowler, S. J., Hashimoto, S., Horvath, I., Howarth, P., Krug, N., Montuschi, P., Sanak, M., Sandstrom, T., Singer, F., Sun, K., Pandis, I., Auffray, C., Sousa, A. R., Adcock, I. M., Chung, K. F., Sterk, P. J., Djukanovic, R., Skipp, P. J., The, U. B. S. G. (2018).
Large-scale label-free quantitative mapping of the sputum proteome.
Journal of Proteome Research 17(6): 2072-2091.
doi: 10.1021/acs.jproteome.8b00018
https://pubs.acs.org/doi/10.1021/acs.jproteome.8b00018

Chen, S., El-Heliebi, A., Schmid, J., Kashofer, K., Czyz, Z. T., Polzer, B. M., Pantel, K., Kroneis, T., Sedlmayr, P. (2018).
Target Cell Pre-enrichment and Whole Genome Amplification for Single Cell Downstream Characterization.
JoVE135.
doi: 10.3791/56394
https://www.jove.com/video/56394/target-cell-pre-enrichment-whole-genome-amplification-for-single-cell

De Meulder, B., Lefaudeux, D., Bansal, A. T., Mazein, A., Chaiboonchoe, A., Ahmed, H., Balaur, I., Saqi, M., Pellet, J., Ballereau, S., Lemonnier, N., Sun, K., Pandis, I., Yang, X., Batuwitage, M., Kretsos, K., van Eyll, J., Bedding, A., Davison, T., Dodson, P., Larminie, C., Postle, A., Corfield, J., Djukanovic, R., Chung, K. F., Adcock, I. M., Guo, Y. K., Sterk, P. J., Manta, A., Rowe, A., Baribaud, F., Auffray, C., Group, U. B. S., the e, T. C. (2018).
A computational framework for complex disease stratification from multiple large-scale datasets.
BMC Systems Biology 12(1): 60. 
doi: 10.1186/s12918-018-0556-z
https://bmcsystbiol.biomedcentral.com/articles/10.1186/s12918-018-0556-z

Fayyad, A., Lapp, S., Risha, E., Pfankuche, V. M., Rohn, K., Barthel, Y., Schaudien, D., Baumgartner, W., Puff, C. (2018).
Matrix metalloproteinases expression in spontaneous canine histiocytic sarcomas and its xenograft model.
Veterinary Immunology and Immunopathology 198: 54-64.
doi: 10.1016/j.vetimm.2018.03.002
https://www.sciencedirect.com/science/article/pii/S0165242717305123?via%3Dihub

Feldmann, J., Bluemlein, K., Krupp, E. M., Mueller, M., Wood, B. A. (2018).
Metallomics study in plants exposed to arsenic, mercury, selenium and sulphur.
Advances in Experimental Medicine and Biology 1055: 67-100.
doi: 10.1007/978-3-319-90143-5_4
https://link.springer.com/chapter/10.1007%2F978-3-319-90143-5_4

Gotzmann, G., Portillo, J., Wronski, S., Kohl, Y., Gorjup, E., Schuck, H., Rögner, F. H., Müller, M., Chaberny, I. F., Schönfelder, J., Wetzel, C. (2018).
Low-energy electron-beam treatment as alternative for on-site sterilization of highly functionalized medical products – A feasibility study.
Radiation Physics and Chemistry 150: 9-19.
doi: 10.1016/j.radphyschem.2018.04.008 
https://www.sciencedirect.com/science/article/pii/S0969806X17313051

Greulich, T., Hohlfeld, J. M., Neuser, P., Lueer, K., Klemmer, A., Schade-Brittinger, C., Harnisch, S., Garn, H., Renz, H., Homburg, U., Renz, J., Kirsten, A., Pedersen, F., Müller, M., Vogelmeier, C. F., Watz, H. (2018).
A GATA3-specific DNAzyme attenuates sputum eosinophilia in eosinophilic COPD patients: a feasibility randomized clinical trial.
Respiratory Research 19(1): 55.
doi: 10.1186/s12931-018-0751-x
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-018-0751-x

Hoffmann, M., Galle, J. (2018).
Stochastic system identification without an a priori chosen kinetic model-exploring feasible cell regulation with piecewise linear functions.
NPJ Systems Biology and Applications 4: 15.
doi: 10.1038/s41540-018-0049-0 
https://www.nature.com/articles/s41540-018-0049-0

Holz, O., Heusser, K., Müller, M., Windt, H., Schwarz, K., Schindler, C., Tank, J., Hohlfeld, J. M., Jordan, J. (2018).
Airway and systemic inflammatory responses to ultrafine carbon black particles and ozone in older healthy subjects.
Journal of Toxicology and Environmental Health. Part A 81(13): 576-588.
doi: 10.1080/15287394.2018.1463331 https://www.tandfonline.com/doi/full/10.1080/15287394.2018.1463331

Jevnikar, Z., Ostling, J., Ax, E., Calven, J., Thorn, K., Israelsson, E., Oberg, L., Singhania, A., Lau, L. C. K., Wilson, S. J., Ward, J. A., Chauhan, A., Sousa, A. R., De Meulder, B., Loza, M. J., Baribaud, F., Sterk, P. J., Chung, K. F., Sun, K., Guo, Y., Adcock, I. M., Payne, D., Dahlen, B., Chanez, P., Shaw, D. E., Krug, N., Hohlfeld, J. M., Sandstrom, T., Djukanovic, R., James, A., Hinks, T. S. C., Howarth, P. H., Vaarala, O., van Geest, M., Olsson, H. K., group, U. B. s. (2018).
Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.
Journal of Allergy and Clinical Immunology [Epub ahead of print].
doi: 10.1016/j.jaci.2018.05.026
https://www.sciencedirect.com/science/article/pii/S0091674918308479

Konerding, W. S., Froriep, U. P., Kral, A., Baumhoff, P. (2018).
New thin-film surface electrode array enables brain mapping with high spatial acuity in rodents.
Scientific Reports 8(1): 3825. doi: 10.1038/s41598-018-22051-z
https://www.nature.com/articles/s41598-018-22051-z

Küppers, L., Holz, O., Schuchardt, S., Gottlieb, J., Fuge, J., Greer, M., Hohlfeld, J. (2018).
Breath volatile organic compounds of lung transplant recipients with and without chronic lung allograft dysfunction.
J Breath Res [Epub ahead of print].
doi: 10.1088/1752-7163/aac5af
http://iopscience.iop.org/article/10.1088/1752-7163/aac5af

Laux, P., Riebeling, C., Booth, A. M., Brain, J. D., Brunner, J., Cerrillo, C., Creutzenberg, O., Estrela-Lopis, I., Gebel, T., Johanson, G., Jungnickel, H., Kock, H., Tentschert, J., Tlili, A., Schäffer, A., Sips, A. J. A. M., Yokel, R. A., Luch, A. (2018). 
Challenges in characterizing the environmental fate and effects of carbon nanotubes and inorganic nanomaterials in aquatic systems.
Environmental Science: Nano 5(1): 48-63.
doi: 10.1039/c7en00594f
http://pubs.rsc.org/en/content/articlelanding/2018/en/c7en00594f#!divAbstract

Lindner, K., Webering, S., Stroebele, M., Bockhorn, H., Hansen, T., König, P., Fehrenbach, H. (2018). 
Low dose carbon black nanoparticle exposure does not aggravate allergic airway inflammation in mice irrespective of the presence of surface polycyclic aromatic hydrocarbons.
Nanomaterials (Basel) 8(4).
doi: 10.3390/nano8040213
http://www.mdpi.com/2079-4991/8/4/213

Lorentzen, A., Becker, P. F., Kosla, J., Saini, M., Weidele, K., Ronchi, P., Klein, C., Wolf, M. J., Geist, F., Seubert, B., Ringelhan, M., Mihic-Probst, D., Esser, K., Roblek, M., Kuehne, F., Bianco, G., O'Connor, T., Müller, Q., Schuck, K., Lange, S., Hartmann, D., Spaich, S., Gross, O., Utikal, J., Haferkamp, S., Sprick, M. R., Damle-Vartak, A., Hapfelmeier, A., Hüser, N., Protzer, U., Trumpp, A., Saur, D., Vartak, N., Klein, C. A., Polzer, B., Borsig, L., Heikenwalder, M. (2018).
Single cell polarity in liquid phase facilitates tumour metastasis.
Nat Commun 9(1): 887.
doi: 10.1038/s41467-018-03139-6
https://www.nature.com/articles/s41467-018-03139-6

Lüke, F., Blazquez, R., Yamaci, R. F., Lu, X., Pregler, B., Hannus, S., Menhart, K., Hellwig, D., Wester, H. J., Kropf, S., Heudobler, D., Grosse, J., Moosbauer, J., Hutterer, M., Hau, P., Riemenschneider, M. J., Bayerlova, M., Bleckmann, A., Polzer, B., Beissbarth, T., Klein, C. A., Pukrop, T. (2018).
Isolated metastasis of an EGFR-L858R-mutated NSCLC of the meninges: the potential impact of CXCL12/CXCR4 axis in EGFRmut NSCLC in diagnosis, follow-up and treatment.
Oncotarget 9(27): 18844-18857.
doi: 10.18632/oncotarget.24787 
http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=view&path[]=24787&path[]=77733

Mang, S., Braun, A., Pairet, N., Lamb, D. J. (2018).
Importance of the IL-1 Axis in Haemophilus influenzae-stimulated M1 Macrophages Driving Transepithelial Signaling.
American Journal of Respiratory Cell and Molecular Biology 58(3): 412-415.
doi: 10.1165/rcmb.2017-0283LE
https://www.atsjournals.org/doi/10.1165/rcmb.2017-0283LE 

Pohlmann, G., Hohlfeld, J. M., Haidl, P., Pankalla, J., Cloes, R. M. (2018).
Assessment of the power required for optimal use of current inhalation devices.
Journal of Aerosol Medicine and Pulmonary Drug Delivery [Epub ahead of print].
doi: 10.1089/jamp.2017.1376
https://www.liebertpub.com/doi/full/10.1089/jamp.2017.1376

Ritter, D., Bitsch, A., Elend, M., Schuchardt, S., Hansen, T., Brodbeck, C., Knebel, J., Fuchs, A., Gronewold, C., Fautz, R. (2018).
Development and evaluation of an in vitro test system for toxicity screening of aerosols released from consumer products and first application to aerosols from a hair straightening process.
Applied In Vitro Toxicology [Epub ahead of print].
doi: 10.1089/aivt.2017.0036
https://www.liebertpub.com/doi/10.1089/aivt.2017.0036

Rogol, A. D., Tkachenko, N., Badorrek, P., Hohlfeld, J. M., Bryson, N. (2018).
Phase 1 pharmacokinetics and phase 3 efficacy of testosterone nasal gel in subjects with seasonal allergies.
Can Urol Assoc J 12(7).
doi: 10.5489/cuaj.4898
http://www.cuaj.ca/index.php/journal/issue/archive

Schwarz, K., Pappa, G., Miertsch, H., Scheel, J., Koch, W. (2018).
A methodology for the assessment of inhalation exposure to aluminium from antiperspirant sprays.
Archives of Toxicology 92(4): 1383-1392.
doi: 10.1007/s00204-017-2151-2
https://link.springer.com/article/10.1007%2Fs00204-017-2151-2

Takahashi, K., Pavlidis, S., Ng Kee Kwong, F., Hoda, U., Rossios, C., Sun, K., Loza, M., Baribaud, F., Chanez, P., Fowler, S. J., Horvath, I., Montuschi, P., Singer, F., Musial, J., Dahlen, B., Dahlen, S. E., Krug, N., Sandstrom, T., Shaw, D. E., Lutter, R., Bakke, P., Fleming, L. J., Howarth, P. H., Caruso, M., Sousa, A. R., Corfield, J., Auffray, C., De Meulder, B., Lefaudeux, D., Djukanovic, R., Sterk, P. J., Guo, Y., Adcock, I. M., Chung, K. F., group, o. b. o. t. U. B. s. (2018).
Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis.
European Respiratory Journal 51(5).
doi: 10.1183/13993003.02173-2017
http://erj.ersjournals.com/content/51/5/1702173.long

Tamo, L., Simillion, C., Hibaoui, Y., Feki, A., Gugger, M., Prasse, A., Jager, B., Goldmann, T., Geiser, T., Gazdhar, A. (2017).
Gene network analysis of interstitial macrophages after treatment with induced pluripotent stem cells secretome (iPSC-cm) in the bleomycin injured rat lung.
Stem Cell Rev Rep [Epub ahead of print].
doi: 10.1007/s12015-017-9790-9
https://link.springer.com/article/10.1007%2Fs12015-017-9790-9

Wronski, S., Dannenmaier, J., Schild, S., Macke, O., Müller, L., Burmeister, Y., Seilheimer, B., Müller, M. (2018).
Engystol reduces onset of experimental respiratory syncytial virus-induced respiratory inflammation in mice by modulating macrophage phagocytic capacity.
PloS One 13(4): e0195822.
doi: 10.1371/journal.pone.0195822
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0195822

Ziemann, S., van der Linde, K., Lahrmann, U., Acar, B., Kaschani, F., Colby, T., Kaiser, M., Ding, Y., Schmelz, E., Huffaker, A., Holton, N., Zipfel, C., Doehlemann, G. (2018).
An apoplastic peptide activates salicylic acid signalling in maize.
Nat Plants 4(3): 172-180.
doi: 10.1038/s41477-018-0116-y
https://www.nature.com/articles/s41477-018-0116-y

Zind, L., Troyke, R., Turban, K., Schaudien, D., Baumgärtner, W., Hansmann, F. (2018).
Ein importierter Fall von feliner Leishmaniose in Deutschland und eine Literaturübersicht zur felinen Leishmaniose. [An imported case of feline leishmaniosis in Germany with a literature review on feline leishmaniosis]
Berliner und Munchener Tierarztliche Wochenschrift [Epub ahead of print].
doi: 10.2376/0005-9366-17061

Behr, J., Gunther, A., Bonella, F., Geissler, K., Koschel, D., Kreuter, M., Prasse, A., Schonfeld, N., Sitter, H., Muller-Quernheim, J., Costabel, U.:
German Guideline for Idiopathic Pulmonary Fibrosis - Update on Pharmacological Therapies 2017.
Pneumologie (2018) [Epub ahead of print]
doi: 10.1055/s-0043-123035
https://www.thieme-connect.com/DOI/DOI?10.1055/s-0043-123035

Gutberlet, M., Kaireit, T. F., Voskrebenzev, A., Lasch, F., Freise, J., Welte, T., Wacker, F., Hohlfeld, J. M., Vogel-Claussen, J.:
Free-breathing Dynamic (19)F Gas MR Imaging for Mapping of Regional Lung Ventilation in Patients with COPD.
Radiology, Vol. 286 (2018), No. 3, pp. 1040-1051
doi: 10.1148/radiol.2017170591 
http://pubs.rsna.org/doi/10.1148/radiol.2017170591

Happle, C., Jirmo, A. C., Meyer-Bahlburg, A., Habener, A., Hoymann, H. G., Hennig, C., Skuljec, J., Hansen, G.:
B cells control maternofetal priming of allergy and tolerance in a murine model of allergic airway inflammation.
Journal of Allergy and Clinical Immunology, Vol. 141 (2018), No. 2, pp. 685-696 e686. 
doi: 10.1016/j.jaci.2017.03.051
https://www.sciencedirect.com/science/article/pii/S009167491730920X?via%3Dihub

Hohlfeld, J. M., Vogel-Claussen, J., Biller, H., Berliner, D., Berschneider, K., Tillmann, H. C., Hiltl, S., Bauersachs, J., Welte, T.:
Effect of lung deflation with indacaterol plus glycopyrronium on ventricular filling in patients with hyperinflation and COPD (CLAIM): a double-blind, randomised, crossover, placebo-controlled, single-centre trial.
Lancet Respir Med (2018) [Epub ahead of print]. 
doi: 10.1016/S2213-2600(18)30054-7
http://www.thelancet.com/journals/lanres/article/PIIS2213-2600(18)30054-7/fulltext

Hücker, S. M., Vanderhaeghen, S., Abellan-Schneyder, I., Wecko, R., Simon, S., Scherer, S., Neuhaus, K.:
A novel short L-arginine responsive protein-coding gene (laoB) antiparallel overlapping to a CadC-like transcriptional regulator in Escherichia coli O157:H7 Sakai originated by overprinting.
BMC Evolutionary Biology, Vol. 18 (2018), No. 1, p. 21
doi: 10.1186/s12862-018-1134-0
https://bmcevolbiol.biomedcentral.com/articles/10.1186/s12862-018-1134-0

Juling, S., Bohmert, L., Lichtenstein, D., Oberemm, A., Creutzenberg, O., Thunemann, A. F., Braeuning, A., Lampen, A.:
Comparative proteomic analysis of hepatic effects induced by nanosilver, silver ions and nanoparticle coating in rats.
Food and Chemical Toxicology, Vol. 113 (2018), pp. 255-266. 
doi: 10.1016/j.fct.2018.01.056
https://www.sciencedirect.com/science/article/pii/S0278691518300620?via%3Dihub

Laux, P., Tentschert, J., Riebeling, C., Braeuning, A., Creutzenberg, O., Epp, A., Fessard, V., Haas, K. H., Haase, A., Hund-Rinke, K., Jakubowski, N., Kearns, P., Lampen, A., Rauscher, H., Schoonjans, R., Stormer, A., Thielmann, A., Muhle, U., Luch, A.:
Nanomaterials: certain aspects of application, risk assessment and risk communication.
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Neehus, A. L., Lam, J., Haake, K., Merkert, S., Schmidt, N., Mucci, A., Ackermann, M., Schubert, M., Happle, C., Kühnel, M. P., Blank, P., Philipp, F., Goethe, R., Jonigk, D., Martin, U., Kalinke, U., Baumann, U., Schambach, A., Roesler, J., Lachmann, N.:
Impaired IFNgamma-Signaling and Mycobacterial Clearance in IFNgammaR1-Deficient Human iPSC-Derived Macrophages.
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Neuhaus, V., Danov, O., Konzok, S., Obernolte, H., Dehmel, S., Braubach, P., Jonigk, D., Fieguth, H.-G., Zardo, P., Warnecke, G., Martin, C., Braun, A., Sewald, K.: 
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Schwotzer, D., Niehof, M., Schaudien, D., Kock, H., Hansen, T., Dasenbrock, C., Creutzenberg, O.:
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Toropova, A. P., Toropov, A. A., Marzo, M., Escher, S. E., Dorne, J. L., Georgiadis, N., Benfenati, E.: 
The application of new HARD-descriptor available from the CORAL software to building up NOAEL models.
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Ulmer, A., Dietz, K., Werner-Klein, M., Hafner, H. M., Schulz, C., Renner, P., Weber, F., Breuninger, H., Rocken, M., Garbe, C., Fierlbeck, G., Klein, C. A.:
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Werner-Klein, M., Scheitler, S., Hoffmann, M., Hodak, I., Dietz, K., Lehnert, P., Naimer, V., Polzer, B., Treitschke, S., Werno, C., Markiewicz, A., Weidele, K., Czyz, Z., Hohenleutner, U., Hafner, C., Haferkamp, S., Berneburg, M., Rummele, P., Ulmer, A., Klein, C. A.:
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International Consensus Statement on Allergy and Rhinology: Allergic Rhinitis.
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Yu, Y., Schleich, K., Yue, B., Ji, S., Lohneis, P., Kemper, K., Silvis, M. S., Qutob, N., van Rooijen, E., Werner-Klein, M., Li, L., Dhawan, D., Meierjohann, S., Reimann, M., Elkahloun, A., Treitschke, S., Dorken, B., Speck, C., Mallette, F. A., Zon, L. I., Holmen, S. L., Peeper, D. S., Samuels, Y., Schmitt, C. A., Lee, S.:
Targeting the Senescence-Overriding Cooperative Activity of Structurally Unrelated H3K9 Demethylases in Melanoma.
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Oltmanns, J., Licht, O., Bitsch, A., Bohlen, M. L., Escher, S. E., Silano, V., MacLeod, M., Serafimova, R., Kass, G. E. N., Merten, C.:
Development of a novel scoring system for identifying emerging chemical risks in the food chain.
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Hoffmann, M., Pasch, S., Schamberger, T., Maneck, M., Möhlendick, B., Schumacher, S., Brockhoff, G., Knoefel, WT., Izbicki, J., Polzer, B., Stoecklein, N. H., Klein, C. A.:
Diagnostic pathology of early systemic cancer: ERBB2 gene amplification in single disseminated cancer cells determines patient survival in operable esophageal cancer.
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Epub 2017 Nov 30

Lorentzen, A., Becker, P. F., Kosla, J., Saini, M., Weidele, K., Ronchi, P., Klein, C., Wolf, M. J., Geist, F., Seubert, B., Ringelhan, M., Mihic-Probst, D., Esser, K., Roblek, M., Kuehne, F., Bianco, G., O´Connor, T., Müller, Q., Schuck, K., Lange, S., Hartmann, D., Spaich, S., Groß, O., Utikal, J., Haferkamp, S., Sprick, M. R., Damle-Vartak, A., Hapfelmeier, A., Hüser, N., Protzer, U., Trumpp, A., Saur, D., Vartak, N., Klein, C. A., Polzer, B., Borsig, L. & Heikenwalder, M.:
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