Fraunhofer Institute for Toxicology and Experimental Medicine
Fraunhofer Institute for Toxicology and Experimental Medicine

Publications of Fraunhofer ITEM

Publications 2022

  • Abdul Nabi Ali, A., Alam, M., Klein, S. C., Behmann, N., Krauss, J. K., Doll, T., Blume, H., Schwabe, K. (2022). Predictive accuracy of CNN for cortical oscillatory activity in an acute rat model of parkinsonism. Neural Netw 146: 334-340. doi: 10.1016/j.neunet.2021.11.025 https://www.sciencedirect.com/science/article/abs/pii/S0893608021004664?via%3Dihub
  • Arbustini, E., Behr, E. R., Carrier, L., van Duijn, C., Evans, P., Favalli, V., van der Harst, P., Haugaa, K. H., Jondeau, G., Kaab, S., Kaski, J. P., Kavousi, M., Loeys, B., Pantazis, A., Pinto, Y., Schunkert, H., Di Toro, A., Thum, T., Urtis, M., Waltenberger, J., Elliott, P. (2022). Interpretation and actionability of genetic variants in cardiomyopathies: a position statement from the European Society of Cardiology Council on cardiovascular genomics. European Heart Journal [Epub ahead of print]: 17 p. doi: 10.1093/eurheartj/ehab895 https://academic.oup.com/eurheartj/advance-article/doi/10.1093/eurheartj/ehab895/6516788  - Open Access
  • Badi, Y. E., Pavel, A. B., Pavlidis, S., Riley, J. H., Bates, S., Kermani, N. Z., Knowles, R., Kolmert, J., Wheelock, C. E., Worsley, S., Uddin, M., Alving, K., Bakke, P. S., Behndig, A., Caruso, M., Chanez, P., Fleming, L. J., Fowler, S. J., Frey, U., Howarth, P., Horvath, I., Krug, N., Maitland-van der Zee, A. H., Montuschi, P., Roberts, G., Sanak, M., Shaw, D. E., Singer, F., Sterk, P. J., Djukanovic, R., Dahlen, S. E., Guo, Y. K., Chung, K. F., Guttman-Yassky, E., Adcock, I. M., Group, U. B. S. (2022). Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma. Journal of Allergy and Clinical Immunology 149(1): 89-101. doi: 10.1016/j.jaci.2021.04.010 https://www.sciencedirect.com/science/article/abs/pii/S0091674921006485?via%3Dihub
  • Baron, Y., Sens, J., Lange, L., Nassauer, L., Klatt, D., Hoffmann, D., Kleppa, M.-J., Barbosa, P. V., Keisker, M., Steinberg, V., Suerth, J. D., Vondran, F. W. R., Meyer, J., Morgan, M., Schambach, A., Galla, M. (2022). Improved alpharetrovirus-based Gag.MS2 particles for efficient and transient delivery of CRISPR-Cas9 into target cells. Molecular Therapy - Nucleic Acids 27: 810-823. doi: 10.1016/j.omtn.2021.12.033 https://www.sciencedirect.com/science/article/pii/S216225312100336X?via%3Dihub  - Open Access
  • Batke, M., Damm, G., Foth, H., Freyberger, A., Gebel, T., Gundert-Remy, U., Hengstler, J., Mangerich, A., Partosch, F., Rohl, C., Schupp, T., Wollin, K. M. (2022). The EU chemicals strategy for sustainability: critical reflections on proposed regulatory changes for endocrine disruptors and mixture toxicity. Archives of Toxicology [Epub ahead of print]. doi: 10.1007/s00204-022-03227-z https://link.springer.com/article/10.1007/s00204-022-03227-z  -
  • Bei, Y., Lu, D., Bar, C., Chatterjee, S., Costa, A., Riedel, I., Mooren, F. C., Zhu, Y., Huang, Z., Wei, M., Hu, M., Liu, S., Yu, P., Wang, K., Thum, T., Xiao, J. (2022). miR-486 attenuates cardiac ischemia/reperfusion injury and mediates the beneficial effect of exercise for myocardial protection. Molecular Therapy 30(4): 1675-1691. doi: 10.1016/j.ymthe.2022.01.031 https://www.sciencedirect.com/science/article/abs/pii/S1525001622000314?via%3Dihub -
  • Biener, M., Giannitsis, E., Thum, T., Bar, C., Stoyanov, K. M., Salbach, C., de Gonzalo-Calvo, D., Frey, N., Mueller-Hennessen, M. (2022). Prognostic value of circulating microRNAs compared to high-sensitivity troponin T in patients presenting with suspected acute coronary syndrome to the emergency department. Clinical Biochemistry 99: 9-16. doi: 10.1016/j.clinbiochem.2021.09.009 https://www.sciencedirect.com/science/article/abs/pii/S0009912021002502?via%3Dihub
  • Burzlaff, A., Creutzenberg, O., Schaudien, D., Viegas, V., Danzeisen, R., Warheit, D. (2022). A tiered approach to investigate the inhalation toxicity of cobalt substances. Tier 4: Effects from a 28-day inhalation toxicity study with tricobalt tetraoxide in rats. Regulatory Toxicology and Pharmacology 130: 105129. doi: 10.1016/j.yrtph.2022.105129 https://www.sciencedirect.com/science/article/pii/S0273230022000162?via%3Dihub  - Open Access
  • Carstensen, S., Benediktus, E., Litzenburger, T., Hohlfeld, J. M., Muller, M. (2022). Basophil activation test: Assay precision and BI 1002494 SYK inhibition in healthy and mild asthmatics. Cytometry A 101(1): 86-94. doi: 10.1002/cyto.a.24338 https://onlinelibrary.wiley.com/doi/10.1002/cyto.a.24338  - Open Access
  • Costa, A., Cushman, S., Haubner, B. J., Derda, A. A., Thum, T., Bar, C. (2022). Neonatal injury models: integral tools to decipher the molecular basis of cardiac regeneration. Basic Research in Cardiology 117(1): 26. doi: 10.1007/s00395-022-00931-w https://link.springer.com/article/10.1007/s00395-022-00931-w - Open Access
  • Creutzenberg, O., Oliveira, H., Farcal, L., Schaudien, D., Mendes, A., Menezes, A. C., Tischler, T., Burla, S., Ziemann, C. (2022). PLATOX: Integrated In Vitro/In Vivo Approach for Screening of Adverse Lung Effects of Graphene-Related 2D Nanomaterials. Nanomaterials (Basel) 12(8). doi: 10.3390/nano12081254 https://www.mdpi.com/2079-4991/12/8/1254  - Open Access
  • Davidson, S. M., Boulanger, C. M., Aikawa, E., Badimon, L., Barile, L., Binder, C. J., Brisson, A., Buzas, E., Emanueli, C., Jansen, F., Katsur, M., Lacroix, R., Lim, S. K., Mackman, N., Mayr, M., Menasche, P., Nieuwland, R., Sahoo, S., Takov, K., Thum, T., Vader, P., Wauben, M. H. M., Witwer, K., Sluijter, J. P. G. (2022). Methods for the identification and characterization of extracellular vesicles in cardiovascular studies - from exosomes to microvesicles. Cardiovascular Research [Epub ahead of print]. doi: 10.1093/cvr/cvac031 https://academic.oup.com/cardiovascres/advance-article-abstract/doi/10.1093/cvr/cvac031/6553781?redirectedFrom=fulltext
  • de Boer, R. A., Heymans, S., Backs, J., Carrier, L., Coats, A. J. S., Dimmeler, S., Eschenhagen, T., Filippatos, G., Gepstein, L., Hulot, J. S., Knoll, R., Kupatt, C., Linke, W. A., Seidman, C. E., Tocchetti, C. G., van der Velden, J., Walsh, R., Seferovic, P. M., Thum, T. (2022). Targeted therapies in genetic dilated and hypertrophic cardiomyopathies: from molecular mechanisms to therapeutic targets. A position paper from the Heart Failure Association (HFA) and the Working Group on Myocardial Function of the European Society of Cardiology (ESC). European Journal of Heart Failure 24(3): 406-420. doi: 10.1002/ejhf.2414 https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2414 - Open Access
  • De Sadeleer, L. J., Verleden, S. E., Schupp, J. C., McDonough, J. E., Goos, T., Yserbyt, J., Bargagli, E., Rottoli, P., Kaminski, N., Prasse, A., Wuyts, W. A. (2022). BAL Transcriptomes Characterize Idiopathic Pulmonary Fibrosis Endotypes With Prognostic Impact. Chest [Epub ahead of print]. doi: 10.1016/j.chest.2021.12.668 https://www.sciencedirect.com/science/article/abs/pii/S0012369222000538?via%3Dihub
  • Elrayess, M. A., Cyprian, F. S., Abdallah, A. M., Emara, M. M., Diboun, I., Anwardeen, N., Schuchardt, S., Yassine, H. M. (2022). Metabolic Signatures of Type 2 Diabetes Mellitus and Hypertension in COVID-19 Patients With Different Disease Severity. Frontiers in Medicine 8. doi: 10.3389/fmed.2021.788687 https://www.frontiersin.org/articles/10.3389/fmed.2021.788687/full  - Open Access
  • Escher, S. E., Aguayo-Orozco, A., Benfenati, E., Bitsch, A., Braunbeck, T., Brotzmann, K., Bois, F., van der Burg, B., Castel, J., Exner, T., Gadaleta, D., Gardner, I., Goldmann, D., Hatley, O., Golbamaki, N., Graepel, R., Jennings, P., Limonciel, A., Long, A., Maclennan, R., Mombelli, E., Norinder, U., Jain, S., Capinha, L. S., Taboureau, O. T., Tolosa, L., Vrijenhoek, N. G., van Vugt-Lussenburg, B. M. A., Walker, P., van de Water, B., Wehr, M., White, A., Zdrazil, B., Fisher, C. (2022). Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action. Toxicology in Vitro 79: 105269. doi: 10.1016/j.tiv.2021.105269 https://www.sciencedirect.com/science/article/abs/pii/S0887233321001946  -
  • Färber, I., Kruger, J., Rocha, C., Armando, F., von Kockritz-Blickwede, M., Pohlmann, S., Braun, A., Baumgartner, W., Runft, S., Kruger, N. (2022). Investigations on SARS-CoV-2 Susceptibility of Domestic and Wild Animals Using Primary Cell Culture Models Derived from the Upper and Lower Respiratory Tract. Viruses 14(4). doi: 10.3390/v14040828 https://www.mdpi.com/1999-4915/14/4/828 - Open Access
  • Friedrich, M., Pfeifer, G., Binder, S., Aigner, A., Vollmer Barbosa, P., Makert, G. R., Fertey, J., Ulbert, S., Bodem, J., Konig, E. M., Geiger, N., Schambach, A., Schilling, E., Buschmann, T., Hauschildt, S., Koehl, U., Sewald, K. (2022). Selection and Validation of siRNAs Preventing Uptake and Replication of SARS-CoV-2. Front Bioeng Biotechnol 10: 801870. doi: 10.3389/fbioe.2022.801870 https://www.frontiersin.org/articles/10.3389/fbioe.2022.801870/full  - Open Access
  • Funk, J., Ruehl-Fehlert, C., Leonard, C., Kellner, R., Rittinghausen, S. (2022). Immunohistochemical Characterization of Proliferative Lesions in the Thymus of Aging CD-1 Mice From Two Studies on the RITA Database, With Special Reference to the Perivascular Space. Toxicologic Pathology [Epub ahead of print]: 1926233221082972. doi: 10.1177/01926233221082972 https://journals.sagepub.com/doi/10.1177/01926233221082972  - Open Access
  • Gonzalez, A., Richards, A. M., de Boer, R. A., Thum, T., Arfsten, H., Hulsmann, M., Falcao-Pires, I., Diez, J., Foo, R. S. Y., Chan, M. Y., Aimo, A., Anene-Nzelu, C. G., Abdelhamid, M., Adamopoulos, S., Anker, S. D., Belenkov, Y., Gal, T. B., Cohen-Solal, A., Bohm, M., Chioncel, O., Delgado, V., Emdin, M., Jankowska, E. A., Gustafsson, F., Hill, L., Jaarsma, T., Januzzi, J. L., Jhund, P. S., Lopatin, Y., Lund, L. H., Metra, M., Milicic, D., Moura, B., Mueller, C., Mullens, W., Nunez, J., Piepoli, M. F., Rakisheva, A., Ristic, A. D., Rossignol, P., Savarese, G., Tocchetti, C. G., Van Linthout, S., Volterrani, M., Seferovic, P., Rosano, G., Coats, A. J. S., Bayes-Genis, A. (2022). Cardiac remodelling - Part 1: From cells and tissues to circulating biomarkers. A review from the Study Group on Biomarkers of the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure [Epub ahead of print]. doi: 10.1002/ejhf.2493 https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2493  - Open Access
  • Grinberg, M., Stober, R. M., Edlund, K., Rempel, E., Godoy, P., Reif, R., Widera, A., Madjar, K., Schmidt-Heck, W., Marchan, R., Sachinidis, A., Spitkovsky, D., Hescheler, J., Carmo, H., Arbo, M. D., van de Water, B., Wink, S., Vinken, M., Rogiers, V., Escher, S., Hardy, B., Mitic, D., Apic, G., Myatt, G., Waldmann, T., Mardinoglu, A., Damm, G., Seehofer, D., Nussler, A., Weiss, T. S., Oberemm, A., Lampen, A., Schaap, M. M., Luijten, M., van Steeg, H., Thasler, W. E., Kleinjans, J. C. S., Stierum, R. H., Leist, M., Rahnenfuhrer, J., Hengstler, J. G. (2022). Correction to: Toxicogenomics directory of chemically exposed human hepatocytes. Archives of Toxicology 96(3): 945-946. doi: 10.1007/s00204-021-03206-w https://link.springer.com/article/10.1007/s00204-021-03206-w  - Open Access
  • Henschenmacher, B., Bitsch, A., de Las Heras Gala, T., Forman, H. J., Fragoulis, A., Ghezzi, P., Kellner, R., Koch, W., Kuhne, J., Sachno, D., Schmid, G., Tsaioun, K., Verbeek, J., Wright, R. (2022). The effect of radiofrequency electromagnetic fields (RF-EMF) on biomarkers of oxidative stress in vivo and in vitro: A protocol for a systematic review. Environ Int 158: 106932. doi: 10.1016/j.envint.2021.106932 https://www.sciencedirect.com/science/article/pii/S0160412021005572  - Open Access
  • Heratizadeh, A., Roesner, L. M., Traidl, S., Moitinho-Silva, L., Ellinghusen, B., Rodriguez, E., Harder, I., Sapak, M., Weidinger, S., Badorrek, P., Hohlfeld, J. M., Werfel, T. (2022). Basic skin therapy effects on skin inflammation and microbiome composition in patients with atopic dermatitis after challenges with grass pollen. Journal of the European Academy of Dermatology and Venereology [Epub ahead of print]. doi: 10.1111/jdv.17966 https://onlinelibrary.wiley.com/doi/10.1111/jdv.17966  
  • Herrera, V. L. M., Walkey, A. J., Nguyen, M. Q., Gromisch, C. M., Mosaddhegi, J. Z., Gromisch, M. S., Jundi, B., Lukassen, S., Carstensen, S., Denis, R., Belkina, A. C., Baron, R. M., Pinilla-Vera, M., Mueller, M., Kimberly, W. T., Goldstein, J. N., Lehmann, I., Shih, A. R., Eils, R., Levy, B. D., Ruiz-Opazo, N. (2022). A targetable 'rogue' neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS. Scientific Reports 12(1): 5583. doi: 10.1038/s41598-022-09343-1 https://www.nature.com/articles/s41598-022-09343-1  - Open Access
  • Hoda, U., Pavlidis, S., Bansal, A. T., Takahashi, K., Hu, S., Ng Kee Kwong, F., Rossios, C., Sun, K., Bhavsar, P., Loza, M., Baribaud, F., Chanez, P., Fowler, S. J., Horvath, I., Montuschi, P., Singer, F., Musial, J., Dahlen, B., Krug, N., Sandstrom, T., Shaw, D. E., Lutter, R., Fleming, L. J., Howarth, P. H., Caruso, M., Sousa, A. R., Corfield, J., Auffray, C., De Meulder, B., Lefaudeux, D., Dahlen, S. E., Djukanovic, R., Sterk, P. J., Guo, Y., Adcock, I. M., Chung, K. F., group, U. B. s. (2022). Clinical and transcriptomic features of persistent exacerbation-prone severe asthma in U-BIOPRED cohort. Clin Transl Med 12(4): e816. doi: 10.1002/ctm2.816 https://onlinelibrary.wiley.com/doi/10.1002/ctm2.816  - Open Access
  • Holz, O., Muller, M., Carstensen, S., Olin, A. C., Hohlfeld, J. M. (2022). Inflammatory cytokines can be monitored in exhaled breath particles following segmental and inhalation endotoxin challenge in healthy volunteers. Scientific Reports 12(1): 5620. doi: 10.1038/s41598-022-09399-z https://www.nature.com/articles/s41598-022-09399-z - Open Access
  • Holz, O., van Vorstenbosch, R., Guenther, F., Schuchardt, S., Trinkmann, F., van Schooten, F. J., Smolinska, A., Hohlfeld, J. M. (2022). Changes of breath volatile organic compounds in healthy volunteers following segmental and inhalation endotoxin challenge. Journal of Breath Research 16(3). doi: 10.1088/1752-7163/ac6359 https://iopscience.iop.org/article/10.1088/1752-7163/ac6359  - Open Access
  • Janssen, P., Barton, G., Kietzmann, M., Meissner, J. (2022). Treatment of pigs with enrofloxacin via different oral dosage forms - environmental contaminations and resistance development of Escherichia coli. Journal of Veterinary Science [Epub ahead of print]. doi: 10.4142/jvs.21216 https://vetsci.org/DOIx.php?id=10.4142/jvs.21216  - Open Access
  • Kreutzer, F. P., Meinecke, A., Mitzka, S., Hunkler, H. J., Hobuss, L., Abbas, N., Geffers, R., Weusthoff, J., Xiao, K., Jonigk, D. D., Fiedler, J., Thum, T. (2022). Development and characterization of anti-fibrotic natural compound similars with improved effectivity. Basic Research in Cardiology 117(1): 9. doi: 10.1007/s00395-022-00919-6 https://link.springer.com/article/10.1007/s00395-022-00919-6  - Open Access
  • Kreutzer, F. P., Meinecke, A., Schmidt, K., Fiedler, J., Thum, T. (2022). Alternative strategies in cardiac preclinical research and new clinical trial formats. Cardiovascular Research 118(3): 746-762. doi: 10.1093/cvr/cvab075 https://academic.oup.com/cardiovascres/article/118/3/746/6162160  - Open Access
  • Leonardy, J., Bar, C. (2022). Editorial Research Topic: Non-coding RNA as Therapeutic Target: A Game Changer in Cardiac Regenerative Strategies? Frontiers in Physiology 12: 822280. doi: 10.3389/fphys.2021.822280 https://www.frontiersin.org/articles/10.3389/fphys.2021.822280/full  - Open Access
  • Makarewich, C. A., Thum, T. (2022). Exercise-Induced Long Noncoding RNAs As New Players in Cardiac Hypertrophy. Circulation 145(16): 1234-1237. doi: 10.1161/CIRCULATIONAHA.122.059278 https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.059278
  • Malik, M. N. H., Waqas, S. F., Zeitvogel, J., Cheng, J., Geffers, R., Gouda, Z. A., Elsaman, A. M., Radwan, A. R., Schefzyk, M., Braubach, P., Auber, B., Olmer, R., Musken, M., Roesner, L. M., Gerold, G., Schuchardt, S., Merkert, S., Martin, U., Meissner, F., Werfel, T., Pessler, F. (2022). Congenital deficiency reveals critical role of ISG15 in skin homeostasis. Journal of Clinical Investigation 132(3). doi: 10.1172/JCI141573 https://www.jci.org/articles/view/141573  - Open Access
  • Mederer, T., Elsner, F., Robold, T., Grosser, C., Neu, R., Ried, M., Bleicher, S., Schamberger, T., Blochberger, I., Hofmann, H. S., Klein, C. A. (2022). EpCAM-positive disseminated cancer cells in bone marrow impact on survival of early-stage NSCLC patients. Lung Cancer 167: 73-77. doi: 10.1016/j.lungcan.2022.02.008 https://www.sciencedirect.com/science/article/pii/S0169500222003646?via%3Dihub  - Open Access
  • Metzenmacher, M., Hegedus, B., Forster, J., Schramm, A., Horn, P. A., Klein, C. A., Bielefeld, N., Ploenes, T., Aigner, C., Theegarten, D., Schildhaus, H. U., Siveke, J. T., Schuler, M., Lueong, S. S. (2022). Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer. Translational Oncology 15(1): 101279. doi: 10.1016/j.tranon.2021.101279 https://www.sciencedirect.com/science/article/pii/S1936523321002709?via%3Dihub  - Open Access
  • Meumann, N., Schmithals, C., Elenschneider, L., Hansen, T., Balakrishnan, A., Hu, Q., Hook, S., Schmitz, J., Brasen, J. H., Franke, A. C., Olarewaju, O., Brandenberger, C., Talbot, S. R., Fangmann, J., Hacker, U. T., Odenthal, M., Ott, M., Piiper, A., Buning, H. (2022). Hepatocellular Carcinoma Is a Natural Target for Adeno-Associated Virus (AAV) 2 Vectors. Cancers 14(2). doi: 10.3390/cancers14020427 https://www.mdpi.com/2072-6694/14/2/427  - Open Access
  • Mullens, W., Martens, P., Testani, J. M., Tang, W. H. W., Skouri, H., Verbrugge, F. H., Fudim, M., Iacoviello, M., Franke, J., Flammer, A. J., Palazzuoli, A., Barragan, P. M., Thum, T., Marcos, M. C., Miro, O., Rossignol, P., Metra, M., Lassus, J., Orso, F., Jankowska, E. A., Chioncel, O., Milicic, D., Hill, L., Seferovic, P., Rosano, G., Coats, A., Damman, K. (2022). Renal effects of guideline directed medical therapies in heart failure - a consensus document from the Heart Failure Association of the European Society of Cardiology. European Journal of Heart Failure [Epub ahead of print]. doi: 10.1002/ejhf.2471 https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2471 - Open Access
  • Obernolte, H., Niehof, M., Braubach, P., Fieguth, H. G., Jonigk, D., Pfennig, O., Tschernig, T., Warnecke, G., Braun, A., Sewald, K. (2022). Cigarette smoke alters inflammatory genes and the extracellular matrix - investigations on viable sections of peripheral human lungs. Cell and Tissue Research 387(2): 249-260. doi: 10.1007/s00441-021-03553-1 https://link.springer.com/article/10.1007/s00441-021-03553-1  - Open Access
  • Obert, A. J., Gutberlet, M., Kern, A. L., Kaireit, T. F., Glandorf, J., Moher Alsady, T., Wacker, F., Hohlfeld, J. M., Vogel-Claussen, J. (2022). Examining lung microstructure using (19) F MR diffusion imaging in COPD patients. Magnetic Resonance in Medicine [Epub ahead of print]. doi: 10.1002/mrm.29237 https://onlinelibrary.wiley.com/doi/10.1002/mrm.29237  - Open Access
  • Preuss, E. B., Schubert, S., Werlein, C., Stark, H., Braubach, P., Hofer, A., Plucinski, E. K. J., Shah, H. R., Geffers, R., Sewald, K., Braun, A., Jonigk, D. D., Kuhnel, M. P. (2022). The challenge of long-term cultivation of human precision-cut lung slices. American Journal of Pathology 192(2): 239-253. doi: 10.1016/j.ajpath.2021.10.020 https://www.sciencedirect.com/science/article/pii/S0002944021004818?via%3Dihub  - Open Access
  • Rohl, C., Batke, M., Damm, G., Freyberger, A., Gebel, T., Gundert-Remy, U., Hengstler, J. G., Mangerich, A., Matthiessen, A., Partosch, F., Schupp, T., Wollin, K. M., Foth, H. (2022). New aspects in deriving health-based guidance values for bromate in swimming pool water. Archives of Toxicology [Epub ahead of print]. doi: 10.1007/s00204-022-03255-9 https://link.springer.com/article/10.1007/s00204-022-03255-9  - Open Access
  • Runft, S., Farber, I., Kruger, J., Kruger, N., Armando, F., Rocha, C., Pohlmann, S., Burigk, L., Leitzen, E., Ciurkiewicz, M., Braun, A., Schneider, D., Baumgartner, L., Freisleben, B., Baumgartner, W. (2022). Alternatives to animal models and their application in the discovery of species susceptibility to SARS-CoV-2 and other respiratory infectious pathogens: A review. Veterinary Pathology [Epub ahead of print]: 3009858211073678. doi: 10.1177/03009858211073678 https://journals.sagepub.com/doi/10.1177/03009858211073678  -
  • Saeb, A., Grundmann, S. M., Gessner, D. K., Schuchardt, S., Most, E., Wen, G., Eder, K., Ringseis, R. (2022). Feeding of cuticles from Tenebrio molitor larvae modulates the gut microbiota and attenuates hepatic steatosis in obese Zucker rats. Food & Function [Epub ahead of print]. doi: 10.1039/d1fo03920b https://pubs.rsc.org/en/Content/ArticleLanding/2022/FO/D1FO03920B  -
  • Sauerhering, L., Kuznetsova, I., Kupke, A., Meier, L., Halwe, S., Rohde, C., Schmidt, J., Morty, R. E., Danov, O., Braun, A., Vadasz, I., Becker, S., Herold, S. (2022). Cyclosporin A Reveals Potent Antiviral Effects in Preclinical Models of SARS-CoV-2 Infection. American Journal of Respiratory and Critical Care Medicine [Epub ahead of print]. doi: 10.1164/rccm.202108-1830LE https://www.atsjournals.org/doi/10.1164/rccm.202108-1830LE  - Open Access
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