Fraunhofer Institute for Toxicology and Experimental Medicine
Fraunhofer Institute for Toxicology and Experimental Medicine

Publications of Fraunhofer ITEM

Publications 2021

  • Abdo, M., Uddin, M., Goldmann, T., Marwitz, S., Bahmer, T., Holz, O., Kirsten, A. M., Trinkmann, F., von Mutius, E., Kopp, M., Hansen, G., Rabe, K. F., Watz, H., Pedersen, F., group, A. s. (2021). "Raised sputum extracellular DNA confers lung function impairment and poor symptom control in an exacerbation-susceptible phenotype of neutrophilic asthma." Respiratory Research 22(1): 167. doi: 10.1186/s12931-021-01759-z https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-021-01759-z  - Open Access
  • Alahmadi, F. H., Simpson, A. J., Gomez, C., Ericsson, M., Thörngren, J. O., Wheelock, C., Shaw, D. E., Fleming, L. J., Roberts, G., Riley, J., Bates, S., Sousa, A. R., Knowles, R., Bansal, A. T., Corfield, J., Pandis, I., Sun, K., Bakke, P. S., Caruso, M., Chanez, P., Dahlén, B., Horvath, I., Krug, N., Montuschi, P., Singer, F., Wagers, S., Adcock, I. M., Djukanovic, R., Chung, K. F., Sterk, P. J., Dahlen, S. E., Fowler, S. J. (2021). "Medication Adherence in Patients With Severe Asthma Prescribed Oral Corticosteroids in the U-BIOPRED Cohort." Chest [Epub ahead of print]. doi: 10.1016/j.chest.2021.02.023 https://www.sciencedirect.com/science/article/abs/pii/S0012369221002889?via%3Dihub
  • Almeida, L., Dhillon-LaBrooy, A., Castro, C. N., Adossa, N., Carriche, G. M., Guderian, M., Lippens, S., Dennerlein, S., Hesse, C., Lambrecht, B. N., Berod, L., Schauser, L., Blazar, B. R., Kalesse, M., Muller, R., Moita, L. F., Sparwasser, T. (2021). "Ribosome-Targeting Antibiotics Impair T Cell Effector Function and Ameliorate Autoimmunity by Blocking Mitochondrial Protein Synthesis." Immunity 54(1): 68-83 e66. doi: 10.1016/j.immuni.2020.11.001 https://www.sciencedirect.com/science/article/pii/S1074761320304660  - Open Access
  • Al-Mekhlafi, A., Suhs, K. W., Schuchardt, S., Kuhn, M., Muller-Vahl, K., Trebst, C., Skripuletz, T., Klawonn, F., Stangel, M., Pessler, F. (2021). "Elevated Free Phosphatidylcholine Levels in Cerebrospinal Fluid Distinguish Bacterial from Viral CNS Infections." Cells 10(5): 1115. doi: 10.3390/cells10051115 https://www.mdpi.com/2073-4409/10/5/1115 - Open Access
  • Armando, F., Fayyad, A., Arms, S., Barthel, Y., Schaudien, D., Rohn, K., Gambini, M., Lombardo, M. S., Beineke, A., Baumgartner, W., Puff, C. (2021). "Intratumoral Canine Distemper Virus Infection Inhibits Tumor Growth by Modulation of the Tumor Microenvironment in a Murine Xenograft Model of Canine Histiocytic Sarcoma." Int J Mol Sci 22(7): 3578. doi: 10.3390/ijms22073578 https://www.mdpi.com/1422-0067/22/7/3578  - Open Access
  • Asperger, H., Cieslik, J. P., Alberter, B., Kostler, C., Polzer, B., Muller, V., Pantel, K., Riethdorf, S., Koch, A., Hartkopf, A., Wiesmuller, L., Janni, W., Schochter, F., Franken, A., Niederacher, D., Fehm, T., Neubauer, H. (2021). "ViBiBa: Virtual BioBanking for the DETECT multicenter trial program - decentralized storage and processing." Translational Oncology 14(8): 101132. doi: 10.1016/j.tranon.2021.101132 https://www.sciencedirect.com/science/article/pii/S1936523321001248?via%3Dihub - Open Access
  • Babayev, R., Wiese, L. (2021). Benchmarking Classifiers on Medical Datasets of UEA Archive. Proceedings of AI Health WWW 2021: International Workshop on AI in Health: Transferring and Integrating Knowledge for Better Health (AI Health WWW 2021). Ljubljana, Slovenia April 19, 2021, ACM - Association for Computing Machinery.
  • Badi, Y. E., Pavel, A. B., Pavlidis, S., Riley, J. H., Bates, S., Kermani, N. Z., Knowles, R., Kolmert, J., Wheelock, C. E., Worsley, S., Uddin, M., Alving, K., Bakke, P. S., Behndig, A., Caruso, M., Chanez, P., Fleming, L. J., Fowler, S. J., Frey, U., Howarth, P., Horváth, I., Krug, N., Maitland-van der Zee, A. H., Montuschi, P., Roberts, G., Sanak, M., Shaw, D. E., Singer, F., Sterk, P. J., Djukanovic, R., Dahlen, S. E., Guo, Y. K., Chung, K. F., Guttman-Yassky, E., Adcock, I. M. (2021). "Mapping atopic dermatitis and anti-IL-22 response signatures to type 2-low severe neutrophilic asthma." Journal of Allergy and Clinical Immunology [Epub ahead of print]. doi: 10.1016/j.jaci.2021.04.010 https://www.sciencedirect.com/science/article/abs/pii/S0091674921006485?via%3Dihub
  • Badimon, L., Robinson, E. L., Jusic, A., Carpusca, I., de Windt, L. J., Emanueli, C., Ferdinandy, P., Gu, W., Gyongyosi, M., Hackl, M., Karaduzovic-Hadziabdic, K., Lustrek, M., Martelli, F., Nham, E., Potocnjak, I., Satagopam, V., Schneider, R., Thum, T., Devaux, Y., CA, E. U.-C. C. A. (2021). "Cardiovascular rna markers and artificial intelligence may improve covid-19 outcome: position paper from the eu-cardiorna cost action ca17129." Cardiovascular Research 117(8): 1823-1840. doi: 10.1093/cvr/cvab094 https://academic.oup.com/cardiovascres/advance-article/doi/10.1093/cvr/cvab094/6220322 Open Access
  • Batke, M., Afrapoli, F. M., Kellner, R., Rathman, J., Yang, C., Cronin, M., Escher, S. (2021). "Threshold of Toxicological Concern -an update for non-genotoxic carcinogens." Frontiers in Toxicology [Epub ahead of print]. doi: 10.3389/ftox.2021.688321 https://www.frontiersin.org/articles/10.3389/ftox.2021.688321/full - Open Access
  • Behr, J., Gunther, A., Bonella, F., Dinkel, J., Fink, L., Geiser, T., Geissler, K., Glaser, S., Handzhiev, S., Jonigk, D., Koschel, D., Kreuter, M., Leuschner, G., Markart, P., Prasse, A., Schonfeld, N., Schupp, J. C., Sitter, H., Muller-Quernheim, J., Costabel, U. (2021). "S2K Guideline for Diagnosis of Idiopathic Pulmonary Fibrosis." Respiration 100(3): 1-34. doi: 10.1159/000512315 https://www.karger.com/Article/FullText/512315 - Open Access
  • Behr, J., Prasse, A., Kreuter, M., Johow, J., Rabe, K. F., Bonella, F., Bonnet, R., Grohe, C., Held, M., Wilkens, H., Hammerl, P., Koschel, D., Blaas, S., Wirtz, H., Ficker, J. H., Neumeister, W., Schönfeld, N., Claussen, M., Kneidinger, N., Frankenberger, M., Hummler, S., Kahn, N., Tello, S., Freise, J., Welte, T., Neuser, P., Günther, A. (2021). "Pirfenidone in patients with progressive fibrotic interstitial lung diseases other than idiopathic pulmonary fibrosis (RELIEF): a double-blind, randomised, placebo-controlled, phase 2b trial." The Lancet. Respiratory medicine 9(5): 476-486. doi: 10.1016/s2213-2600(20)30554-3 https://www.sciencedirect.com/science/article/abs/pii/S2213260020305543?via%3Dihub
  • Beier, J., Watz, H., Diamant, Z., Hohlfeld, J. M., Singh, D., Pinot, P., Jones, I., Tillmann, H. C. (2021). "Lung function improvements following inhaled indacaterol/glycopyrronium/mometasone furoate are independent of dosing time in asthma patients: a randomised trial." ERJ Open Res 7(2). doi: 10.1183/23120541.00425-2020 https://openres.ersjournals.com/content/7/2/00425-2020  - Open Access
  • Bernstein, D. M., Toth, B., Rogers, R. A., Kunzendorf, P., Phillips, J. I., Schaudien, D. (2021). "Final results from a 90-day quantitative inhalation toxicology study evaluating the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to TiO2, chrysotile, crocidolite or amosite asbestos: Histopathological examination, confocal microscopy and collagen quantification of the lung and pleural cavity." Toxicology and Applied Pharmacology [Epub ahead of print]: 115598. doi: 10.1016/j.taap.2021.115598 https://www.sciencedirect.com/science/article/pii/S0041008X21002052?via%3Dihub
  • Bessler, S., Hess, K., Weigt, H., von Ramin, M. (2021). "Biological transformation - battery protection inspired by wound healing." Bioinspir Biomim [Epub ahead of print]. doi: 10.1088/1748-3190/ac1249 https://iopscience.iop.org/article/10.1088/1748-3190/ac1249  - Open Access
  • Bialek-Waldmann, J. K., Domning, S., Esser, R., Glienke, W., Mertens, M., Aleksandrova, K., Arseniev, L., Kumar, S., Schneider, A., Koenig, J., Theobald, S. J., Tsay, H. C., Cornelius, A. D. A., Bonifacius, A., Eiz-Vesper, B., Figueiredo, C., Schaudien, D., Talbot, S. R., Bleich, A., Spineli, L. M., von Kaisenberg, C., Clark, C., Blasczyk, R., Heuser, M., Ganser, A., Kohl, U., Farzaneh, F., Stripecke, R. (2021). "Induced dendritic cells co-expressing GM-CSF/IFN-alpha/tWT1 priming T and B cells and automated manufacturing to boost GvL." Mol Ther Methods Clin Dev 21: 621-641. doi: 10.1016/j.omtm.2021.04.004 https://www.sciencedirect.com/science/article/pii/S232905012100070X?via%3Dihub - Open Access
  • Biener, M., Giannitsis, E., Thum, T., Bar, C., Costa, A., Andrzejewski, T., Stoyanov, K. M., Vafaie, M., Meder, B., Katus, H. A., de Gonzalo-Calvo, D., Mueller-Hennessen, M. (2021). "Diagnostic value of circulating microRNAs compared to high-sensitivity troponin T for the detection of non-ST-segment elevation myocardial infarction." Eur Heart J Acute Cardiovasc Care [Epub ahead of print]. doi: 10.1093/ehjacc/zuaa034 https://academic.oup.com/ehjacc/advance-article-abstract/doi/10.1093/ehjacc/zuaa034/6062698?redirectedFrom=fulltext
  • Boogaard, P. J., Buschmann, J., Fuhst, R., Blumlein, K., Koch, W., Schaudien, D., Schwarz, K., McAlinden, C., Deferme, L., Vaissiere, M., Ketelslegers, H. B., Steneholm, A. (2021). "Prenatal developmental toxicity studies on fumes from oxidised asphalt (OA) in the rat." Reproductive Toxicology 102: 67-79. doi: 10.1016/j.reprotox.2021.03.003 https://www.sciencedirect.com/science/article/abs/pii/S0890623821000472?via%3Dihub
  • Boogaard, P. J., Buschmann, J., Fuhst, R., Blumlein, K., Schwarz, K., Schaudien, D., Koch, W., McAlinden, C., Deferme, L., Vaissiere, M., Ketelslegers, H. B., Steneholm, A. (2021). "Prenatal developmental toxicity studies on fumes from bitumen in the rat." Reproductive Toxicology 99: 15-26. doi: 10.1016/j.reprotox.2020.11.009 https://www.sciencedirect.com/science/article/pii/S0890623820302689?via%3Dihub  - Open Access
  • Brandes, R. P., Dueck, A., Engelhardt, S., Kaulich, M., Kupatt, C., De Angelis, M. T., Leisegang, M. S., le Noble, F., Moretti, A., Muller, O. J., Skryabin, B. V., Thum, T., Wurst, W. (2021). "DGK and DZHK position paper on genome editing: basic science applications and future perspective." Basic Research in Cardiology 116(1): 2. doi: 10.1007/s00395-020-00839-3 https://link.springer.com/article/10.1007/s00395-020-00839-3
  • Buchmueller, J., Sprenger, H., Ebmeyer, J., Rasinger, J. D., Creutzenberg, O., Schaudien, D., Hengstler, J. G., Guenther, G., Braeuning, A., Hessel-Pras, S. (2021). "Pyrrolizidine alkaloid-induced transcriptomic changes in rat lungs in a 28-day subacute feeding study." Archives of Toxicology [Epub ahead of print]. doi: 10.1007/s00204-021-03108-x https://link.springer.com/article/10.1007/s00204-021-03108-x  - Open Access
  • Buchmüller, J., Ebmeyer, J., Sprenger, H., D., R. J., Hengstler, J., Schaudien, D., Creutzenberg, O., Braeuning, A., Hessel-Pras, S. (2021). "Pyrrolizidine alkaloids induce different transcription patterns in rat liver, lung, and kidney." Naunyn-Schmiedeberg's Archives of Pharmacology - Abstracts of the 87th Annual Meeting of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) With contribution of the Arbeitsgemeinschaft für Angewandte Humanpharmakologie e. V. (AGAH) 394 (Suppl 1): S21, Abstract 69. - Abstract
  • Carstensen, S., Benediktus, E., Litzenburger, T., Hohlfeld, J. M., Muller, M. (2021). "Basophil activation test: Assay precision and BI 1002494 SYK inhibition in healthy and mild asthmatics." Cytometry A [Epub ahead of print]. doi: 10.1002/cyto.a.24338 https://onlinelibrary.wiley.com/doi/10.1002/cyto.a.24338 - Open Access
  • Carstensen, S., Holz, O., Hohlfeld, J. M., Muller, M. (2021). "Quantitative analysis of endotoxin-induced inflammation in human lung cells by Chipcytometry." Cytometry A [Epub ahead of print]. doi: 10.1002/cyto.a.24352 https://onlinelibrary.wiley.com/doi/10.1002/cyto.a.24352  - Open Access
  • Chapman, K. R., Watz, H., Singh, D., Hohlfeld, J. M., Diamant, Z., Jones, I., Tillmann, H. C., Nikolaev, I. (2021). "Lung Function Normalisation with Indacaterol Acetate/Glycopyrronium Bromide/Mometasone Furoate in Patients with Asthma." Clinical Drug Investigation 41(5): 489-492. doi: 10.1007/s40261-021-01033-6 https://link.springer.com/article/10.1007%2Fs40261-021-01033-6  - Open Access
  • Chatterjee, S., Hofer, T., Costa, A., Lu, D., Batkai, S., Gupta, S. K., Bolesani, E., Zweigerdt, R., Megias, D., Streckfuss-Bomeke, K., Brandenberger, C., Thum, T., Bar, C. (2021). "Telomerase therapy attenuates cardiotoxic effects of doxorubicin." Molecular Therapy 29(4): 1395-1410. doi: 10.1016/j.ymthe.2020.12.035 https://www.sciencedirect.com/science/article/pii/S1525001620307280?via%3Dihub
  • Creutzenberg, O. H., Hammann, V., Wolf, S. (2021). "Toxicokinetics of a Be-7 Tagged Carbon Black Sample following Intratracheal Instillation into Rat Lungs." The Toxicologist Supplement to Toxicological Sciences - SOT- Society of Toxicology, Annual Meeting and ToxExpo Virtual Event, March 2021 180(S1): 116, Abstract PS 2191. - Abstract
  • Dahlke, J., Schott, J. W., Vollmer Barbosa, P., Klatt, D., Selich, A., Lachmann, N., Morgan, M., Moritz, T., Schambach, A. (2021). "Efficient Genetic Safety Switches for Future Application of iPSC-Derived Cell Transplants." J Pers Med 11(6). doi: 10.3390/jpm11060565 https://www.mdpi.com/2075-4426/11/6/565  - Open Access
  • Derlin, T., Jaeger, B., Jonigk, D., Apel, R. M., Freise, J., Shin, H. O., Weiberg, D., Warnecke, G., Ross, T. L., Wester, H. J., Seeliger, B., Welte, T., Bengel, F. M., Prasse, A. (2021). "Clinical Molecular Imaging of Pulmonary CXCR4 Expression to Predict Outcome of Pirfenidone Treatment in Idiopathic Pulmonary Fibrosis." Chest 159(3): 1094-1106. doi: 10.1016/j.chest.2020.08.2043 https://www.sciencedirect.com/science/article/pii/S001236922034229X?via%3Dihub  - Open Access
  • Eggenhofer, E., Groell, A., Junger, H., Kasi, A., Kroemer, A., Geissler, E. K., Schlitt, H. J., Scherer, M. N. (2021). "Steatotic Livers Are More Susceptible to Ischemia Reperfusion Damage after Transplantation and Show Increased gammadelta T Cell Infiltration." Int J Mol Sci 22(4): 2036. doi: 10.3390/ijms22042036 https://www.mdpi.com/1422-0067/22/4/2036  - Open Access
  • Escher, S. (2021). "Use of Case Studies for Increasing Confidence in Non-validated Approaches in Next-Generation Risk Assessment." The Toxicologist Supplement to Toxicological Sciences - SOT- Society of Toxicology, Annual Meeting and ToxExpo Virtual Event, March 2021 180(S1): 70, Abstract W 1313. - Abstract
  • Escher, S. E., Bitsch, A. (2021). Read-Across Methodology in Toxicological Risk Assessment. In: Regulatory Toxicology. p 1-14.
  • Esteve-Codina, A., Hofer, T. P., Burggraf, D., Heiss-Neumann, M. S., Gesierich, W., Boland, A., Olaso, R., Bihoreau, M. T., Deleuze, J. F., Moeller, W., Schmid, O., Soler Artigas, M., Renner, K., Hohlfeld, J. M., Welte, T., Fuehner, T., Jerrentrup, L., Koczulla, A. R., Greulich, T., Prasse, A., Muller-Quernheim, J., Gupta, S., Brightling, C., Subramanian, D. R., Parr, D. G., Kolsum, U., Gupta, V., Barta, I., Dome, B., Strausz, J., Stendardo, M., Piattella, M., Boschetto, P., Korzybski, D., Gorecka, D., Nowinski, A., Dabad, M., Fernandez-Callejo, M., Endesfelder, D., Zu Castell, W., Hiemstra, P. S., Venge, P., Noessner, E., Griebel, T., Heath, S., Singh, D., Gut, I., Ziegler-Heitbrock, L. (2021). "Gender specific airway gene expression in COPD sub-phenotypes supports a role of mitochondria and of different types of leukocytes." Scientific Reports 11(1): 12848. doi: 10.1038/s41598-021-91742-x https://www.nature.com/articles/s41598-021-91742-x  - Open Access
  • Foremny, K., Konerding, W. S., Behrens, A., Baumhoff, P., Froriep, U. P., Kral, A., Doll, T. (2021). "Carbon-Nanotube-Coated Surface Electrodes for Cortical Recordings In Vivo." Nanomaterials (Basel) 11: 1029. doi: 10.3390/nano1104102 https://www.mdpi.com/2079-4991/11/4/1029  - Open Access
  • Friedmann, D., Unger, S., Keller, B., Rakhmanov, M., Goldacker, S., Zissel, G., Frye, B. C., Schupp, J. C., Prasse, A., Warnatz, K. (2021). "Bronchoalveolar Lavage Fluid Reflects a TH1-CD21(low) B-Cell Interaction in CVID-Related Interstitial Lung Disease." Frontiers in Immunology 11: 616832. doi: 10.3389/fimmu.2020.616832 https://www.frontiersin.org/articles/10.3389/fimmu.2020.616832/full  - Open Access
  • Gadaleta, D., Marzo, M., Toropov, A., Toropova, A., Lavado, G. J., Escher, S. E., Dorne, J., Benfenati, E. (2021). "Integrated in silico models for the prediction of no-observed-(adverse)-effect levels and lowest-observed-(adverse)-effect levels in rats for sub-chronic repeated-dose toxicity." Chemical Research in Toxicology 34(2): 247-257. doi: 10.1021/acs.chemrestox.0c00176 https://pubs.acs.org/doi/10.1021/acs.chemrestox.0c00176
  • Garg, A., Seeliger, B., Derda, A. A., Xiao, K., Gietz, A., Scherf, K., Sonnenschein, K., Pink, I., Hoeper, M. M., Welte, T., Bauersachs, J., David, S., Bar, C., Thum, T. (2021). "Circulating cardiovascular microRNAs in critically ill COVID-19 patients." European Journal of Heart Failure 23(3): 468-475. doi: 10.1002/ejhf.2096 https://onlinelibrary.wiley.com/doi/10.1002/ejhf.2096  - Open Access
  • Glaab, T., Braun, A. (2021). "Noninvasive Measurement of Pulmonary Function in Experimental Mouse Models of Airway Disease." Lung 199(3): 255-261. doi: 10.1007/s00408-021-00443-9 https://link.springer.com/article/10.1007%2Fs00408-021-00443-9  - Open Access
  • Gupta, R., Schrooders, Y., Hauser, D., van Herwijnen, M., Albrecht, W., Ter Braak, B., Brecklinghaus, T., Castell, J. V., Elenschneider, L., Escher, S., Guye, P., Hengstler, J. G., Ghallab, A., Hansen, T., Leist, M., Maclennan, R., Moritz, W., Tolosa, L., Tricot, T., Verfaillie, C., Walker, P., van de Water, B., Kleinjans, J., Caiment, F. (2021). "Comparing in vitro human liver models to in vivo human liver using RNA-Seq." Archives of Toxicology 95(2): 573-589. doi: 10.1007/s00204-020-02937-6 https://link.springer.com/article/10.1007/s00204-020-02937-6  - Open Access
  • Habener, A., Happle, C., Grychtol, R. M., Skuljec, J., Busse, M., Daluge, K., Obernolte, H., Sewald, K., Braun, A., Meyer-Bahlburg, A., Hansen, G. (2020). "Regulatory B cells control airway hyperreactivity and lung remodeling in a murine asthma model." Journal of Allergy and Clinical Immunology 147(6): 2281-2294 e2287. doi: 10.1016/j.jaci.2020.09.041 https://www.sciencedirect.com/science/article/abs/pii/S0091674920316341?via%3Dihub
  • Haddad, G., Kolling, M., Wegmann, U. A., Dettling, A., Seeger, H., Schmitt, R., Soerensen-Zender, I., Haller, H., Kistler, A. D., Dueck, A., Engelhardt, S., Thum, T., Mueller, T. F., Wuthrich, R. P., Lorenzen, J. M. (2021). "Renal AAV2-Mediated Overexpression of Long Non-Coding RNA H19 Attenuates Ischemic Acute Kidney Injury Through Sponging of microRNA-30a-5p." Journal of the American Society of Nephrology 32(2): 323-341. doi: 10.1681/ASN.2020060775 https://jasn.asnjournals.org/content/32/2/323.long
  • Hahn, S., Meyer, J., Roitzsch, M., Delmaar, C., Koch, W., Schwarz, J., Heiland, A., Schendel, T., Jung, C., Schlüter, U. (2021). "Modelling Exposure by Spraying Activities—Status and Future Needs." International Journal of Environmental Research and Public Health 18(15). doi: 10.3390/ijerph18157737 https://www.mdpi.com/1660-4601/18/15/7737 - Open Access
  • Hall, D. A., Hanrott, K., Badorrek, P., Berliner, D., Budd, D. C., Eames, R., Powley, W. M., Hewens, D., Siederer, S., Lazaar, A. L., Cahn, A., Hohlfeld, J. M. (2021). "Effects of Recombinant Human Angiotensin-Converting Enzyme 2 on Response to Acute Hypoxia and Exercise: A Randomised, Placebo-Controlled Study." Pulm Ther [Epub ahead of print]. doi: 10.1007/s41030-021-00164-7 https://link.springer.com/article/10.1007/s41030-021-00164-7 - Open Access
  • Hamdani, N., Costantino, S., Mugge, A., Lebeche, D., Tschope, C., Thum, T., Paneni, F. (2021). "Leveraging clinical epigenetics in heart failure with preserved ejection fraction: a call for individualized therapies." European Heart Journal 42(20): 1940-1958. doi: 10.1093/eurheartj/ehab197 https://academic.oup.com/eurheartj/article-abstract/42/20/1940/6264879?redirectedFrom=fulltext
  • Herkt, M., Thum, T. (2021). "Pharmacokinetics and Proceedings in Clinical Application of Nucleic Acid Therapeutics." Molecular Therapy 29(2): 521-539. doi: 10.1016/j.ymthe.2020.11.008 https://www.sciencedirect.com/science/article/abs/pii/S1525001620306067?via%3Dihub
  • Hoffmann, D., Sens, J., Brennig, S., Brand, D., Philipp, F., Vollmer Barbosa, P., Kuehle, J., Steinemann, D., Lenz, D., Buchegger, T., Morgan, M., Falk, C. S., Klein, C., Lachmann, N., Schambach, A. (2021). "Genetic Correction of IL-10RB Deficiency Reconstitutes Anti-Inflammatory Regulation in iPSC-Derived Macrophages." J Pers Med 11(3): 221. doi: 10.3390/jpm11030221 https://www.mdpi.com/2075-4426/11/3/221  - Open Access
  • Hoffmann, M., Hofmann-Winkler, H., Smith, J. C., Krüger, N., Arora, P., Sørensen, L. K., Søgaard, O. S., Hasselstrøm, J. B., Winkler, M., Hempel, T., Raich, L., Olsson, S., Danov, O., Jonigk, D., Yamazoe, T., Yamatsuta, K., Mizuno, H., Ludwig, S., Noé, F., Kjolby, M., Braun, A., Sheltzer, J. M., Pöhlmann, S. (2021). "Camostat mesylate inhibits SARS-CoV-2 activation by TMPRSS2-related proteases and its metabolite GBPA exerts antiviral activity." EBioMedicine 65: 103255. doi: 10.1016/j.ebiom.2021.103255 https://www.sciencedirect.com/science/article/pii/S2352396421000487?via%3Dihub - Open Access
  • Holz, O., Waschki, B., Watz, H., Kirsten, A., Abdo, M., Pedersen, F., Weckmann, M., Fuchs, O., Dittrich, A. M., Hansen, G., Kopp, M. V., von Mutius, E., Rabe, K. F., Hohlfeld, J. M., Bahmer, T., Group, A. S. (2021). "Breath volatile organic compounds and inflammatory markers in adult asthma patients: negative results from the ALLIANCE cohort." European Respiratory Journal 57(2): 2002127. doi: 10.1183/13993003.02127-2020 https://erj.ersjournals.com/content/57/2/2002127  - Open Access
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