Publikationen des Fraunhofer ITEM

Publikationen 2020

  • Bernstein, D. M., Toth, B., Rogers, R. A., Kling, D. E., Kunzendorf, P., Phillips, J. I., Ernst, H. (2020). "Evaluation of the dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to TiO2, chrysotile, crocidolite or amosite asbestos in a 90-day quantitative inhalation toxicology study - Interim results Part 2: Histopathological examination, Confocal microscopy and collagen quantification of the lung and pleural cavity." Toxicology and Applied Pharmacology 387: 114847. doi: 10.1016/j.taap.2019.114847 https://www.sciencedirect.com/science/article/pii/S0041008X19304557?via%3Dihub - Open Access
  • Bernstein, D. M., Toth, B., Rogers, R. A., Kling, D. E., Kunzendorf, P., Phillips, J. I., Ernst, H. (2020). "Evaluation of the exposure, dose-response and fate in the lung and pleura of chrysotile-containing brake dust compared to TiO2, chrysotile, crocidolite or amosite asbestos in a 90-day quantitative inhalation toxicology study - Interim results Part 1: Experimental design, aerosol exposure, lung burdens and BAL." Toxicology and Applied Pharmacology 387: 114856. doi: 10.1016/j.taap.2019.114856 https://www.sciencedirect.com/science/article/pii/S0041008X19304648?via%3Dihub - Open Access
  • Delgado, S. J., Dehmel, S., Twisterling, E., Wichmann, J., Jonigk, D., Warnecke, G., Braubach, P., Fieguth, H. G., Wilkens, L., Dahlmann, F., Kaup, F. J., Eggel, A., Knauf, S., Sewald, K., Braun, A. (2020). "Disruptive anti-IgE inhibitors prevent mast cell-dependent early airway response in viable atopic lung tissue." Journal of Allergy and Clinical Immunology 145(2): 719-722.e711. doi: 10.1016/j.jaci.2019.11.002 https://www.sciencedirect.com/science/article/abs/pii/S009167491931485X?via%3Dihub
  • Escher, S. E., Mangelsdorf, I., Hoffmann-Doerr, S., Partosch, F., Karwath, A., Schroeder, K., Zapf, A., Batke, M. (2020). "Time extrapolation in regulatory risk assessment: The impact of study differences on the extrapolation factors." Regulatory Toxicology and Pharmacology [Epub ahead of print]: 104584. doi: 10.1016/j.yrtph.2020.104584 https://www.sciencedirect.com/science/article/abs/pii/S0273230020300106?via%3Dihub
  • Franken, A., Honisch, E., Reinhardt, F., Meier-Stiegen, F., Yang, L., Jaschinski, S., Esposito, I., Alberter, B., Polzer, B., Huebner, H., Fasching, P. A., Pancholi, S., Martin, L. A., Ruckhaeberle, E., Schochter, F., Tzschaschel, M., Hartkopf, A. D., Mueller, V., Niederacher, D., Fehm, T., Neubauer, H. (2020). "Detection of ESR1 Mutations in Single Circulating Tumor Cells on Estrogen Deprivation Therapy but Not in Primary Tumors from Metastatic Luminal Breast Cancer Patients." J Mol Diagn 22(1): 111-121. doi: 10.1016/j.jmoldx.2019.09.004 https://www.ncbi.nlm.nih.gov/pubmed/31669227
    https://www.sciencedirect.com/science/article/abs/pii/S1525157819304027?via%3Dihub
  • Holz, O., DeLuca, D. S., Roepcke, S., Illig, T., Weinberger, K. M., Schudt, C., Hohlfeld, J. M. (2020). "Smokers with COPD Show a Shift in Energy and Nitrogen Metabolism at Rest and During Exercise." International Journal of Chronic Obstructive Pulmonary Disease 15: 1-13. doi: 10.2147/copd.S217474 https://www.dovepress.com/smokers-with-copd-show-a-shift-in-energy-and-nitrogen-metabolism-at-re-peer-reviewed-fulltext-article-COPD - Open Access
  • Huppertz, C., Jäger, B., Wieczorek, G., Engelhard, P., Oliver, S. J., Bauernfeind, F. G., Littlewood-Evans, A., Welte, T., Hornung, V., Prasse, A. (2020). "The NLRP3 inflammasome pathway is activated in sarcoidosis and involved in granuloma formation." European Respiratory Journal [Epub ahead of print]. doi: 10.1183/13993003.00119-2019 https://erj.ersjournals.com/content/early/2020/01/03/13993003.00119-2019.long
  • Lange, L., Hoffmann, D., Schwarzer, A., Ha, T. C., Philipp, F., Lenz, D., Morgan, M., Schambach, A. (2020). "Inducible Forward Programming of Human Pluripotent Stem Cells to Hemato-endothelial Progenitor Cells with Hematopoietic Progenitor Potential." Stem Cell Reports 14(1): 122-137. doi: 10.1016/j.stemcr.2019.11.005 https://www.sciencedirect.com/science/article/pii/S2213671119304084?via%3Dihub - Open Access
  • Metzenmacher, M., Varaljai, R., Hegedus, B., Cima, I., Forster, J., Schramm, A., Scheffler, B., Horn, P. A., Klein, C. A., Szarvas, T., Reis, H., Bielefeld, N., Roesch, A., Aigner, C., Kunzmann, V., Wiesweg, M., Siveke, J. T., Schuler, M., Lueong, S. S. (2020). "Plasma Next Generation Sequencing and Droplet Digital-qPCR-Based Quantification of Circulating Cell-Free RNA for Noninvasive Early Detection of Cancer." Cancers 12(2). doi: 10.3390/cancers12020353 https://www.mdpi.com/2072-6694/12/2/353 - Open Access
  • Oltmanns, J., Licht, O., Bohlen, M. L., Schwarz, M., Escher, S. E., Silano, V., MacLeod, M., Noteborn, H., Kass, G. E. N., Merten, C. (2020). "Potential emerging chemical risks in the food chain associated with substances registered under REACH." Environ Sci Process Impacts 22(1): 105-120. doi: 10.1039/c9em00369j https://pubs.rsc.org/en/content/articlelanding/2020/EM/C9EM00369J#!divAbstract
  • Quercini, L., Brunetti, J., Riolo, G., Bindi, S., Scali, S., Lampronti, I., D'Aversa, E., Wronski, S., Pollini, S., Gentile, M., Lupetti, P., Rossolini, G. M., Falciani, C., Bracci, L., Pini, A. (2020). "An antimicrobial molecule mitigates signs of sepsis in vivo and eradicates infections from lung tissue." FASEB Journal 34(1): 192-207. doi: 10.1096/fj.201901896RR https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201901896RR
  • Ritter, D., Knebel, J., Niehof, M., Loinaz, I., Marradi, M., Gracia, R., Te Welscher, Y., van Nostrum, C. F., Falciani, C., Pini, A., Strandh, M., Hansen, T. (2020). "In vitro inhalation cytotoxicity testing of therapeutic nanosystems for pulmonary infection." Toxicology in Vitro 63: 104714. doi: 10.1016/j.tiv.2019.104714 https://www.sciencedirect.com/science/article/pii/S0887233319302309?via%3Dihub - Open Access
  • Schupp, J. C., Prasse, A., Erythropel, H. C. (2020). "[E-Cigarettes - Operating Principle, Ingredients, and Associated Acute Lung Injury].
    E-Zigaretten – Funktionsweise, Inhaltsstoffe und die Vaping-assoziierte akute Lungenschädigung." Pneumologie [Epub ahead of print]. doi: 10.1055/a-1078-8126
    https://www.thieme-connect.com/products/ejournals/abstract/10.1055/a-1078-8126 - Open Access