Project archive

Fraunhofer researchers have been investigating a spray product for room conditioning in hairdressing salons. They have carried out in-vitro inhalation experiments to investigate acute effects on the respiratory tract with a battery of tests using cells from human lungs and the P.R.I.T.® ExpoCube® exposure system.

The aim of the MyCellFight project is to develop a fully automated immune chip able to predict the specific immune responses of individuals.

The aim of the 3Rs principle is to avoid animal experiments altogether (replacement), to reduce the number of animals per experiment (reduction) and to keep animal distress to an absolute minimum (refinement).

In clinical settings volunteers inhaled bacterial endotoxin to demonstrate the increase in inflammatory cytokines in exhaled particles.

Fraunhofer ITEM is one of four partners in this project that was initiated by the German Centre for Rail Traffic Research (DZSF). We will be contributing to the following project goals, among others.

As part of the Mono4ERA Project, the European Comission conduct a Feasibility study of an active-substance-based review system (“monographs”) and other potential alternatives for the environmental risk assessment of veterinary medicinal products.

Fraunhofer ITEM is actively involved in the search for new active substances for COVID-19 treatment. For these studies, conducted in cooperation with universities and other institutes, PCLS are prepared from human lung tissue and infected with SARS-CoV-2 in an appropriate laboratory.

Fraunhofer researchers have developed the intuitive, web-based end-to-end pipeline MyDeepLearn. MyDeepLearn links the CNNs in the back end with the web application in the front end.

A bronchoscope is used to apply LPS segmentally in the lungs. Using this provocation model, the researchers investigated the effect of a bradykinin-1 receptor antagonist.

Researchers at Fraunhofer ITEM have significantly developed a model of allergen provocation using allergen solutions.