It is not only our excellent scientists that our success is due to. A broad network, both national and international, and numerous cooperation partners represent a crucial factor in our expertise. Fraunhofer ITEM’s network includes other Fraunhofer Institutes that we collaborate with in Fraunhofer Groups, Alliances and Research Clusters, but also universities, research institutions and companies in Germany and all over the world.
The Fraunhofer-Gesellschaft, headquartered in Germany, is the world’s leading applied research organization. With its focus on developing key technologies that are vital for the future and enabling the commercial exploitation of this work by business and industry, Fraunhofer plays a central role in the innovation process. As a pioneer and catalyst for groundbreaking developments and scientific excellence, Fraunhofer helps shape society now and in the future. Founded in 1949, the Fraunhofer-Gesellschaft currently operates 75 institutes and research institutions throughout Germany. The majority of the organization’s 29,000 employees are qualified scientists and engineers, who work with an annual research budget of 2.8 billion euros. Of this sum, 2.4 billion euros are generated through contract research.
Health research is one of the most multi-faceted future areas of innovation. Smart innovations will have to make a significant contribution to affordable health care and to safeguarding the future of society. The Fraunhofer Group for Health Research pools the expertise and technologies of six institutes in the fields of medicine, pharmacy, biomedical engineering, and biotechnology. The high degree of interdisciplinarity within the Group across the four major thematic areas − Data, Devices, Diagnostics, and Drugs − makes it possible to address trend-setting innovations and achieve noticeable added value for health research and patients.
The primary goal of the Fraunhofer Cluster of Excellence for Immune-Mediated Diseases is the translation of innovative ideas and identified targets into individualized therapies for immune-mediated diseases. The collaborating institutes want to bridge the existing gap from research on novel medications to what is actually available to patients.
In forward-looking projects, three Fraunhofer Institutes – Fraunhofer IME, Fraunhofer IZI, and Fraunhofer ITEM – are pooling their expertise, thereby enabling efficient translation. A substantial gain of knowledge in the pathophysiology of immune diseases will thus be generated, innovative targets will be addressed, and new treatment categories in this therapeutic area will be introduced and established.
Fraunhofer Nanotechnologie FNT is a cooperation of several Fraunhofer units that work together in the business and research field of nanotechnology – from application-oriented research to support and consultancy in the implementation of results in industry. Examples are the development of multifunctional layers for optical applications, automotive construction and the electrical equipment industry or the use of metal and oxidic nanoparticles, carbon nanotubes and nanoplatelets as well as nanocomposites as structural and coating materials and for biomedical applications. Furthermore, issues of toxicology and safe handling of nanoparticles are addressed.
Regional networking is a high priority at Fraunhofer ITEM. This is why we are a partner in the Translational Alliance in Lower Saxony (TRAIN). TRAIN bundles the know-how and infrastructure of university and extra-academic research institutions for the development of active pharmaceutical ingredients and vaccines.
The broad spectrum covers the entire biomedical development chain from basic research to actual applications and opens up new possibilities in biomedicine. What makes TRAIN so special is the two-way scientific exchange: Basic researchers learn from clinicians and can thus gear their work to clinically relevant problems, while clinicians learn about new opportunities for practical applications resulting from biomedical research.
The German Center for Lung Research (DZL) is one of six German Centers for Health Research. It is funded by the German Federal Ministry of Education and Research and the governments of the federal states that are home to the corresponding sites. Within the DZL, basic, disease- and patient-oriented research in the field of respiratory diseases is coordinated and conducted at international top level. Twenty-nine leading German research institutions at five different sites cooperate in the DZL.
Fraunhofer ITEM is a member of the BREATH research network at the Hannover site, where the other partners are the Hannover Medical School, the Center for Health Economics Research Hannover at Leibniz University Hannover, and the CAPNETZ competence network. In addition, there is a close cooperation with the REBIRTH cluster of excellence.
Dr. Annette Bitsch
Working committee on probabilistic exposure and risk assessment “Probabilistische Expositions- und Risikoabschätzung”
Expert panel 110 on cooling lubricants “Kühlschmierstoffe” of the Association of German Engineers (VDI) Technical Division 1 “Production Technology and Manufacturing Methods”
Interim Scientific Adisory Council (iSAC) for the reorganization of the Evidence-Based Toxicology Collaboration (EBTC) at Johns Hopkins Bloomberg School of Public Health
Mentor in the Fraunhofer career program for female scientists TALENTA
Reviewer in the peer-review process for the German Federal Health Bulletin “Bundesgesundheitsblatt”
Reviewer for international journals published by Elsevier (incl. “Regulatory Toxicology and Pharmacology”)
Katharina Blümlein Ph.D.
Working group on analyses in biological materials “Analysen in biologischem Material” of the German Research Foundation (DFG)
Prof. Dr. Armin Braun
MD/Ph.D. commission “Molecular Medicine” of the Hannover Medical School
Scientific advisory committee of the German Society for Allergology and Clinical Immunology (DGAKI)
German Center for Lung Research (DZL)
External assessor for international foundations
Reviewer for international journals in respiratory medicine and immunology (incl. “Journal of Allergy and Clinical Immunology”)
Dr. Otto Creutzenberg
Reviewer for international journals in particle and fiber toxicology (“Particle and Fibre Toxicology”, “Inhalation Toxicology”)
Prof. Dr.-Ing. Theodor Doll
VDE/VDI Society Microelectronics, Microsystems and Precision Engineering GMM, chair of the expert panel on microsystems in medicine/functional surfaces “FA 4.6 Mikrosysteme in der Medizin/Funktionale Oberflächen”
German Society for Biomedical Engineering DGBMT, expert panel on sensor technology ”Sensorik”
Reviewer in the European Commission’s Marie Skłodowska-Curie Actions (MSCA) program, expert in the work packages “Biomedical Technologies” and "Sensors" of the EU Graphene Flagship
ASIIN reviewer for biomedical engineering careers
Guest editor of the journal “Physica Status Solidi (a)”
Uta Dörfel
Working groups on GLP analytics “GLP-Analytik” and medical devices “Medizinprodukte” of the German Quality Management Association (GQMA)
Priv.-Doz. Dr. Jan Fiedler
Ph.D. examination board for "Pharmacology, Toxicology and Clinical Chemistry" at the Hannover Medical School
Program committee for the Ph.D. program "Regenerative Sciences" at the Hannover Biomedical Research School (HBRS)
Working group on vascular biology "Vaskuläre Biologie" (AG 4) of the German Cardiac Society
Reviewer for international journals in cardiovascular research
Prof. Dr. Edward Geissler
Chair of the Ethics Committee of the University of Regensburg
Executive editor of the journals "Transplantation" and "Transplanation direct"
Dr. Jens Gerdelmann
Working groups on GLP quality assurance/monitoring “GLP: Qualitätssicherung/Überwachung”, GCP quality management “GCP-Qualitätsmanagement”, and medical devices "Medizinprodukte" of the German Quality Management Association (GQMA)
Dr. Stefan Hahn
Chair of the German Chemical Society (GDCh) Division of Environmental Chemistry and Ecotoxicology
Working committee on chemical risk assessment of the German Chemical Society (GDCh) division of environmental chemistry and ecotoxicology “Umweltchemie und Ökotoxikologie”
Working group "Exposure models" of ISES Europe (Europe Regional Chapter of the International Society of Exposure Science)
Reviewer for international journals in environmental and exposure sciences (incl. “Integrated Environmental Assessment and Management", "Environmental Science & Technology", "Environmental Toxicology and Chemistry", "Annals of Work Exposures and Health", and "Journal of Exposure Science & Environmental Epidemiology")
Martina Heina
IT division of the International Association for Pharmaceutical Technology (APV)
Dr. Martin Hoffmann
Working group on bioinformatics at Comprehensive Cancer Center Ostbayern (CCCO)
External assessor for the Klaus Tschira Foundation (mathematical oncology)
Reviewer for the international journal "Nature Communications"
Prof. Dr. Jens Hohlfeld
External assessor for the German Research Foundation (DFG)
Steering committee of the research network “Biomedical Research in Endstage And ObsTructive Lung Disease Hannover” (BREATH) within the German Center for Lung Research (DZL)
Board member of the interdisciplinary allergy center of the Hannover Medical School
Reviewer for international journals (incl. "American Journal of Respiratory and Critical Care Medicine", "European Respiratory Journal", and "Journal of Allergy and Clinical Immunology")
Dr. Olaf Holz
IABR (International Association of Breath Research) Standardization Focus Group
Reviewer for international journals (incl. "American Journal of Respiratory and Critical Care Medicine", "Journal of Breath Research", "European Respiratory Journal", "PLOS ONE", "Respiratory Research", and "BMC Pulmonary Medicine")
Dr. Rupert Kellner
Councilor for electronic communication and member of the Executive Board of the European Society of Toxicologic Pathology (ESTP)
Global Editorial and Steering Committee (GESC) for the initiative "International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice" (INHAND)
Prof. Dr. Christoph Klein
External assessor for numerous national and international organizations and foundations: German Research Foundation, German Federal Ministry of Education and Research, Wilhelm Sander Foundation for Cancer Research, ERC, Deutsche Krebshilfe, Christian Doppler Research Association, Dutch Cancer Society, Association for International Cancer Research, EU-FP7, MRC, Cancer Research UK, Kegg-Foundation
Deputy chairman of the scientific committee of Comprehensive Cancer Center Ostbayern (CCCO)
Advisory committee of the Pezcoller Foundation-AACR International Award for Cancer Research Committee
Scientific advisory board of the AIRC (Associazione Italiana per la Ricerca sul Cancro) 5x1000 project "Cancer of Unknown Primary (CUP): the archetype of metastatic disease"
Reviewer for international journals in oncology (incl. “Nature”, “Nature Biotechnology”, “Nature Cell Biology”, “Nature Medicine”, “Cancer Cell”, “Science”, “PNAS”, “American Journal of Pathology”, “Cancer Research”, “Clinical Cancer Research”, “International Journal of Cancer”, “Nucleic Acid Research”, “European Journal of Immunology”, “Lancet Oncology”, “European Journal of Cancer”, “PLOS ONE”, and “Oncotarget”)
Prof. Dr. Wolfgang Koch
Reviewer for international journals in aerosol physics and aerosol technology (incl. “Journal of Aerosol Science”, “Aerosol Science and Technology”, and “Annals of Work Exposures and Health”)
Dr. Imke Korf
Reviewer for international MDPI journals (“Microorganisms” and “Antibiotics”)
Prof. Dr. Norbert Krug
Chair of the Clinical Trial Board of the German Center for Lung Research (DZL)
Steering committee of the research network “Biomedical Research in Endstage And ObsTructive Lung Disease Hannover” (BREATH) within the German Center for Lung Research (DZL)
External assessor for the German Research Foundation (DFG)
Steering committee of the Fraunhofer Research Cluster “Immune-Mediated Diseases” (Fraunhofer CIMD)
Scientific advisory committee of the German Society for Allergology and Clinical Immunology (DGAKI)
DEAL project group of the Alliance of Science Organisations in Germany
Working group “Fraunhofer-Gesellschaft and Deutsche Hochschulmedizin”
Reviewer for international journals in allergology, immunology, and respiratory diseases
Dr. Oliver Licht
Working group on sustainable chemicals policy “Nachhaltige Chemikalienpolitik” of the 8th Lower Saxony Governmental Commission on sustainable environmental policy and digital change
German Federal Institute for Risk Assessment (BfR) Committee for Contaminants in the Food Chain; panel on perfluorinated and polyfluorinated alkyl substances “Per- und Polyfluoralkylsubstanzen (PFAS)”
Expert panel “Basic moduleFraunhofer Group for Life Sciences and perfluorinated tensides” of the German Federal Institute for Risk Assessment’s MEAL (= meals for exposure assessment and analysis of foods) study within the Total Diet Study (TDS) in Germany
Working committee on regulatory toxicology “Regulatorische Toxikologie” of the German Toxicology Society within the German Society of Clinical and Experimental Pharmacology and Toxicology (DGPT)
Public relations delegate of the German Toxicology Society
Dr. Meike Müller
Network of ombudspersons in Lower Saxony
Dr. Falko Partosch
Advisory board of the German Toxicology Society within the German Society of Clinical and Experimental Pharmacology and Toxicology (DGPT)
Working group on hazardous substances "Gefahrstoffe" of Subcommittee II of the Committee for the Protection of Working Mothers of the Federal Office of Family Affairs and Civil Society Functions (BAFzA)
Frank Peinemann
Working group on archiving “Archivierung” of the German Quality Management Association (GQMA)
Dr. Gerhard Pohlmann
International Society for Aerosols in Medicine (ISAM)
Dr. Bernhard Polzer
External assessor for the Wilhelm Sander Foundation for Cancer Research
External assessor for the Swiss Cancer League
Reviewer for international journals in pathology and oncology (“British Journal of Cancer”, “Chemical Science”, “International Journal of Cancer”, “Journal of Histochemistry and Cytochemistry”, “Journal of Visualized Experiments”, “Oncotarget”, “Scientific Reports”, “Expert Reviews of Molecular Diagnostics”, “iScience”, and “Molecular Oncology”)
Prof. Dr. Antje Prasse
External assessor for the German Research Foundation (DFG)
Board member of the Scientific Working Group for the Therapy of Lung Diseases (WATL)
Board member of Deutsche Atemwegsliga e. V.
Board member of the World Association of Sarcoidosis and other Granulomatous Disorders (WASOG)
Coordinator of the ILD group in the European Reference Network on Respiratory Diseases ERN-LUNG
Spokesperson for the disease area “DPLD” in the research network “Biomedical Research in Endstage And ObsTructive Lung Disease Hannover” (BREATH) within the German Center for Lung Research (DZL)
Spokesperson of the Cell Biology Section in the German Respiratory Society (DGP)
Reviewer for international journals (incl. “American Journal of Respiratory and Critical Care Medicine”, “European Respiratory Journal”, “Journal of Clinical Investigation”, “JCI Insights”, “American Journal of Respiratory and Cell Biology”, and “Thorax”)
Associate editor of “PLOS ONE”
Tobias Pukrop
Chairman of the working committee on malignant tumors of the CNS “ZNS Malignome” of the German Society of Hematology and Oncology
Steering board of the working panel on CNS/leptomeningeal spread "ZNS/Meningeosis" of the working group on internal oncology "Arbeitsgemeinschaft Internistische Onkologie (AIO)" of the German Cancer Society
Steering board of the Collaborative Reserach Center/Transregio (SFB/TRR) 305: Striking a moving target: From mechanisms of metastatic colonization to novel systemic therapies
Steering board of the Molecular Tumor Board of the University of Regensburg
Steering board of the Brain Tumor Center (ZHT) of the University of Regensburg
Executive Board of the Bavarian Center for Cancer Research
European Society for Medical Oncology
Priv.-Doz. Dr. Susanne Rittinghausen
Co-optive member of the European Society of Toxicologic Pathology (ESTP) board: representative for nomenclature
“Guess What” committee of the European Society of Toxicologic Pathology (ESTP)
Global Editorial and Steering Committee (GESC) for the initiative "International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice" (INHAND)
INHAND (International Harmonization of Nomenclature and Diagnostic Criteria) organ working groups “Respiratory System”, “Endocrine System”, “Soft Tissue”, and “Special Senses”, and working group “Apoptosis”
Ad-hoc working group on inflammatory parameters and inflammatory effects "Entzündungsparameter – entzündliche Effekte" of the DFG Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission)
Reviewer for the international journals “Toxicologic Pathology” and "Toxicology"
Dirk Schaudien Ph.D.
INHAND (International Harmonization of Nomenclature and Diagnostic Criteria) working groups “Non-rodents: Minipig”, "Respiratory System", and "Skeletal Tissues (Bones, Joints, and Teeth)"
“Pathology 2.0” committee of the European Society of Toxicologic Pathology (ESTP)
“Guess What” committee of the European Society of Toxicologic Pathology (ESTP)
Examination board of the European College of Veterinary Pathology
Dr. Stefanie Scheffler
Working group on e-cigarettes and liquids for e-cigarettes of the DIN Standards Committee "Food and Agricultural Products"
Dr. Sven Schuchardt
Treasurer of the German Society for Metabolome Research
Working group on air analyses “Luftanalysen” of the German Research Foundation (DFG)
Leibniz-Institut für Analytische Wissenschaften – ISAS – e. V. (Leibniz Institute for Analytical Sciences)
Dr. Florian Schulz
DFG Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area (MAK Commission): working group on the definition of threshold limit values for dusts
Committee on Hazardous Substances (AGS) under the German Federal Minister of Labor and Social Affairs: Subcommittee III for the evaluation of hazardous substances “Gefahrstoffbewertung”, working groups on metals and fibers/dust
Advisory Board of the European Certification Board for Mineral Wool Products (EUCEB)
External expert in the quality control committee of the mineral wool quality assurance association "RAL-Güteqemeinschaft Mineralwolle" (GGM)
Dr. Katherina Sewald
Steering group of the workshop “Respiratory Toxicity”
German Center for Lung Research (DZL); Young Scientists committee
Executive committee on basic research in the research network “Biomedical Research in Endstage And ObsTructive Lung Disease Hannover” (BREATH) within the German Center for Lung Research (DZL)
Mentor in the Fraunhofer career program for female scientists TALENTA
External assessor for international research grants
Reviewer for the international journals “Toxicology Letters”, “Toxicology in vitro”, “Nanotoxicology”, “ATOX”, and “PLOS ONE”
Prof. Dr. Dr. Thomas Thum
Scientific Advisory Board (SAB) or pool of experts of numerous national and international organizations: Institut Pasteur (France); Interdisciplinary Center for Clinical Research (IZKF) at RWTH Aachen University; International Scientific Advisory Board (ISAB) of the RECONNECT program (The Netherlands); National Committee for the Protection of Animals Used for Scientific Purposes of the German Federal Institute for Risk Assessment; Novo Nordisk Advisory Board for Cardiovascular Diseases; Lower Saxony Life Science Startup Board
Past Chair of the working group on Myocardial Function (WG 4) of the European Society of Cardiology (ESC)
Board member of the Heart Failure Association (HFA) of the European Society of Cardiology (ESC); HFA representative at the ESC Council on Cardiovascular Genomics; chair of the HFA Basic Science Section
Coordinator of REBIRTH – Research Center for Translational Regenerative Medicine at the Hannover Medical School (previously REBIRTH cluster of excellence “From REgenerative BIology to Recontructive THerapy”)
Chairman of the steering committee of the Hannover Unified Biobank (HUB)
External assessor for numerous national and international organizations and foundations, incl. the European Research Council (ERC), German Research Foundation (DFG), German Cardiac Society (DGK), British Heart Foundation (BHF), French Research Association (ANR), Health Research Board Ireland, Austrian Science Fund (FWF), and Dutch Research Council (NWO)
Consulting editor or member of the editorial board of numerous international journals (incl. “Circulation Research”, “Cardiovascular Research”, “Arteriosclerosis, Thrombosis, and Vascular Biology”, “Basic Research in Cardiology”, “American Journal of Physiology – Heart and Circulatory Physiology”, “PLOS ONE”, “Physiological Genomics”, and “Naunyn-Schmiedeberg’s Archives of Pharmacology”)
International associate editor of the “European Heart Journal”
Prof. Dr. Lena Wiese
Special interest group "Digital Health" and working group "Data Science and Data Engineering" of the German Informatics Society
Dr. Dorothee Winterberg
Working group on respiratory toxicology "Respirationstoxikologie" of the German Toxicology Society (GT)
Association of Inhalation Toxicologists (AIT)
German Center for Lung Research (DZL)
Dr. Sabine Wronski
Reviewer for the international journal “European Respiratory Journal”
Prof. Dr. Holger Ziehr
Association of German Engineers (VDI) committee “Technical Good Manufacturing Practice”
GMP discussion group "GMP-Gesprächskreis" of the Lower Saxony business inspectorate
Center for Pharmaceutical Process Engineering (PVZ) at Technische Universität Braunschweig
BioPharma-Translationsinstitut e. V.
Dr. Christina Ziemann
Chair of the working group on statistics of the German Society for Environmental Mutation Research (GUM)
Working group “Genotoxicity” of the DIN Standards Committee "Water Practice“
Working groups on carcinogenesis “Carcinogenese” and on respiratory toxicology "Respirationstoxikologie" of the German Toxicology Society (GT)
OECD pool of experts of the German Federal Institute for Risk Assessment
External assessor for applications submitted to the German Federal Environmental Foundation
German Pharm-Tox Summit program committee
Reviewer for international journals in genetic toxicology, nanomaterials, and quartz (incl. “Regulatory Toxicology and Pharmacology”)
Bavarian Ministry of Economic Affairs, Regional Development and Energy
Further development of Fraunhofer ITEM in Regensburg
Bavarian Research Foundation
Project: Inhibiting COVID‐19 N-protein-mediated infectivity
HTP screening to identify inhibitors of N-protein function to interfere with genome packaging of SARS-CoV-2
Research consortium on tumor diagnostics for individualized therapy (FORTiTher):
Estimation of individual metastasis risk by analysis of disseminated tumor cells
DFG – German Research Foundation
Selection and adaptation during metastatic cancer progression. FOR 2127, project no. 242727105
Collaborative Reserach Center/Transregio (SFB/TRR) 305: Striking a moving target: From mechanisms of metastatic colonization to novel systemic therapies – subprojects "High-throughput screening assays and readouts for targeting metastatic progression" (A07) and "Novel patient-specific immune competent preclinical in vitro models to study early metastasis" (B17).
Federal Agency for Disruptive Innovation (SPRIND)
iGUARD – integrated Guided Ultrafast Antiviral RNAi Drug Development
Federal Environment Agency
Consideration of disinfection by-products in the context of environmental risk assessment of biocidal products - inventory and development of recommendations for the assessment. R&D project 3718 65 403
Investigation of the pathogenic mechanisms of action of emerging pollen allergens using the example of Ambrosia artemisiifolia. R&D project 3720 62 203 0
Federal Institute for Occupational Safety and Health (BAuA)
Mode of toxic action of nanocarbons. Research project F 2376
Federal Joint Committee/Innovation Committee
PTmHBP – Practicability testing of the magistral production of bacteriophages for the therapy of septic infections of the lower extremity (PhagoFlow)
Federal Ministry for Economic Affairs and Energy, central innovation program for SMEs
Development of an ex-vivo rat lung model for quality assurance of surfactant batches without the need to simulate asphyxia
Federal Ministry of Education and Research (BMBF) framework program “Gesundheitsforschung” (health research)
Collaborative research project: 4-IN
Insect-derived inhalable inhibitors of bacterial virulence for treating lung infections
Collaborative research project: NANOpain
Dendritic NanoAnalgesics without addictive potential for better quality of patient life with for patients with cancer, post-operative and chronic pain. R&D project 16GW0333
Collaborative research project: Phage4Cure
Developing bacteriophages as approved therapy against bacterial infections
Collaborative research project: TPHiPAH
Tryptophan hydroxylase inhibitors as novel therapeutics for pulmonary arterial hypertension
Federal Ministry of Education and Research (BMBF) funding program “Alternatives to Animal Testing”
Project: Inhal-Prädikt
Universally applicable model for prediction of the local efficacy of (inhaled) anti-infectives in the lungs
Federal Ministry of Education and Research (BMBF) funding program DigitalLung
Digital auscultation system for differential diagnosis of lung diseases using machine learning
Federal Ministry of Education and Research (BMBF) funding program “Erforschung von Covid-19 im Zuge des Ausbruchs von Sars-CoV-2” (research on Covid-19 in response to the Sars-CoV-2 outbreak)
RENACO – Repurposing of Nafamostatmesylat for Covid-19 treatment
Federal Ministry of Education and Research (BMBF) funding program "In-vitro Challenge"
ImmunAVATAR: Make your immune system great again
Federal Ministry of Education and Research (BMBF) funding program “Innovative Stammzelltechnologien für die individualisierte Medizin” (innovative stem cell technologies for individualized medicine)
Project: iCARE
Induced pluripotent stem cells for clinically applicable heart repair
Federal Ministry of Education and Research (BMBF) funding program "KMU-innovativ: Medizintechnik" (innovative SMEs: biomedical engineering)
Collaborative project: CTCbySCP
Development of a single cell printer-based method for marker-independent quantification and isolation of vital circulating tumor cells for diagnosis and personalized therapy
Federal Ministry of Education and Research (BMBF) funding program "NanoCare4.0 – application-safe material innovations"
Project: MetalSafety
Development of evaluation concepts for fibrous and granular metal compounds: bioavailability, toxicological efficacy profiles and comparative in vitro, ex vivo and in vivo studies
Project: NanoINHAL
In-vitro test methods for airborne nanomaterials to investigate toxic potential and uptake after inhalation exposure using innovative organ-on-a-chip technology
Federal Ministry of Education and Research (BMBF), German Centers for Health Research (DGZ)
German Centre for Cardiovascular Research (DZHK):
Single-cell RNA sequencing in iPSC-derived nodal and atrial cells from patients with atrial fibrillation
German Center for Lung Research (DZL):
Allergy and asthma
Chronic obstructive pulmonary disease (COPD)
Diffuse parenchymal lung diseases (DPLD)
Federal Ministry of Health
ELISE – Ein Lernendes und Interoperables, Smartes Expertensystem für die pädiatrische Intensivmedizin (a learning and interoperable, smart expert system for pediatric intensive-care medicine)
Federal Office for Radiation Protection
Childhood leukemia – influence of the immune system on the development of the disease (experimental study in a suitable animal model). AG-R-08313/3616S82440
Literature study on the influence of electric, magnetic and electromagnetic fields on oxidative processes in humans and in animal and laboratory studies. Z4/AG-R-08313/3619S82464
Investigation into the occurrence of leukaemia in predisposed animal models exposed to magnetic fields. Z4/AG-R-08313/3620S92410
Systematic review on the influence of electric, magnetic and electromagnetic fields on fertility in humans and in animal and laboratory studies. R&D project 3620S82475
Influence of the inter-frequency magnetic fields of inductive power transmission during charging of electric vehicles on the behaviour of laboratory rodents. AG-R-08319/3620EMF401
Investigation of biological mechanisms of radiation-induced cardiovascular diseases. R&D project 3621S32210
German Centre for Rail Traffic Research at the Federal Railway Authority
Emissions and immissions from railway traffic – air pollutant monitoring and dispersion modeling
Lower Saxony Ministry of Science and Culture
Collaborative project: FibroOmics
Translating Omics studies into clinically relevant insights for lung fibrosis patients
EU project: MDOT (Medical Device Obligations Taskforce)
Establishment of a digital platform for simplified conformity assessment and testing of medical devices, including three demonstrator technologies: Inhalation technology, 3D-printed neural implantats, and coatings for orthopedic prostheses
EU project: RealWorld4Clinic
AI-powered health monitoring for clinical research and cardiology (EIT Health innovation project)
EU project: REMEDIA – RElation exposoME DIseAse
Impact of exposome on the course of lung diseases
EU project (EFSA): Development of roadmaps for action on: New approach methodologies in risk assessment (LOT 2; OC/EFSA/ED/2020/01-02)
EU project (EFSA): EFSA Read-Across
Identification of the applicability domain (in terms of toxicological endpoints and chemical space) for the use of read-across in food safety
EU project (EFSA): Emerging Risks III
Screening for Emerging Chemical Risks in the Food Chain
EU project (EFSA): IUCLID training for EFSA
EU project (Horizon 2020): EU-ToxRisk
An Integrated European ‘Flagship’ Programme Driving Mechanism-based Toxicity Testing and Risk Assessment for the 21st century
EU project (Horizon 2020): Marie Skłodowska-Curie Innovative Training Networks, Magicbullet :: Reloaded
Development and employment of approaches for selective, targeted delivery of a panel of anticancer drugs for directed tumor therapy
EU project (Horizon 2020): REMADYL
Removal of legacy substances from polyvinylchloride (PVC) via a continuous and sustainable extrusion process
EU project (HORIZON 2020): RISK-HUNT3R
RISK assessment of chemicals integrating HUman centric Next generation Testing strategies promoting the 3Rs
EU project (Horizon 2020): TBMED
An open innovation test bed for the development of high-risk medical devices
Translation of the quality-by-design approach of the pharmaceutical industry to biomedical engineering, using several medical devices as examples: bone defect reconstruction materials, keratoprosthesis, and nanoparticles for cancer treatment
EU project (HORIZON 2020): ZeroPM
Zero pollution from persistent, mobile substances
EU project (IMI): eTranSafe
Enhancing translational safety assessment through integrative knowledge management
EU project (IMI): Immune Safety Avatar (imSAVAR)
Nonclinical mimicking of the immune system effects of immunomodulatory therapies
EU project (IMI): PREMIER
Prioritization and risk evaluation of medicines in the environment
EU research cluster: ASPIS
Animal-free Safety assessment of chemicals: Project cluster for Implementation of novel Strategies
Prof. Dr. Armin Braun
TRAIN Academy: professional education program "Translational Research & Medicine: From Idea to Product” (lecturer and person in charge of Module 6 “Preclinical development”)
Hannover Medical School: lectures in the MD/Ph.D. program “Molecular Medicine”
Lower Saxony International Summer Academy in Immunology at the Hannover Medical School: lecture on neuroimmune interactions in allergic asthma in the session “Lung Inflammation, Asthma, Allergy”
University of Leipzig: lecture on methods for testing xenobiotics for their airway sensitization potential in the postgraduate course “Toxicology and Environmental Protection”
Dr. Franziska Breuer
Leuphana University Lüneburg: lectures in module F10 Law, International Regulations and Chemicals Management in the professional Master's program "M.Sc. Sustainable Chemistry"
Dr. Gustav Bruer
University of Veterinary Medicine Hannover: lecture on therapies for airway diseases as part of the lecture on clinical pharmacology and toxicology; lecture on inhalation toxicology within the pharmacological colloquium
Dr. Otto Creutzenberg
University of Leipzig: lecture on inhalation toxicology in the postgraduate course “Toxicology and Environmental Protection”
Universities of Jena/Erfurt, Institute for Pharmacology and Toxicology: lecture on exposure methods/toxicokinetics within the DGPT course “Fundamentals of organ toxicology and organ pathology”
Prof. Dr.-Ing. Theodor Doll
Leibniz University Hannover: lecture on polymers for implant production in the degree course “Biomedical Engineering”
Hannover Medical School: postgraduate training course in nanomedicine
Jade University of Applied Sciences Wilhelmshaven: lecture on biomechanics, breathing and neuro-rehabilitation in the degree course “Medical Technology“
Furtwangen University: lecture on telemetry in medicine (co-lecturer)
TRAIN Academy: lectures on economic aspects in implant development in Module 5 (Medical devices) of the vocational training program “Translational Research and Medicine: From the Idea to the Product“
Priv.-Doz. Dr. Jan Fiedler
Hannover Medical School: lectures in the Master's programs "Biomedicine" and "Biochemistry"; lectures on biochemistry/hormones in the Bachelor's program "Midwifery"; hands-on trainings at the Center of Pharmacology and Toxicology in the Master's program "Biomedicine"
Hannover Medical School, Hannover Biomedical Research School (HBRS): lectures in the Ph.D. programs "Regenerative Science" and "Molecular Medicine"
Imperial College London (UK): lectures in the Master's program "Genes, Drugs and Stem Cells"
Prof. Dr. Edward Geissler
University of Regensburg: lecture on methods in transplantation immunology; practical exercises with models for research on tumor angiogenesis; laboratory course for staff and Ph.D. students; lab meeting with Ph.D. students; Journal Club
Dr. Jens Gerdelmann
TRAIN Academy: lectures on quality management, Good Laboratory Practice (GLP), and clinical testing of medical devices (modules 2.1, 2.6 and 5.8)
Hannover Biomedical Research School (HBRS) at the Hannover Medical School: workshop “Introduction to GLP and GMP”
Dr. Markus Heine
Technische Universität Braunschweig: lectures on applied and technical biochemistry incl. hands-on training
Prof. Dr. Jens Hohlfeld
Hannover Medical School: lectures on allergic respiratory diseases
Dr. Stefan Kirsch
University of Regensburg: lectures and hands-on training in molecular oncology in the degree course “Molecular Medicine”; hands-on training in database research in the degree course “Computational Science”
Prof. Dr. Christoph Klein
University of Regensburg: lectures in pathology, molecular oncology and advanced human genetics (“Cancer metastasis as paradigm of an evolutionary disease process“) in the degree course “Molecular Medicine”; seminar and hands-on training in molecular oncology; lectures on pathology in the degree course “Human Medicine”; methodology seminar "Experiment and analysis" for Ph.D., master, and bachelor students of the Chair of Experimental Medicine and Therapy Research; seminars about "Striking a moving target: From mechanisms of metastatic organ colonisation to novel systemic therapies“ within the Collaborative Reserach Center TRR 305
Ostbayerische Technische Hochschule Regensburg: seminar "How does metastatic dissemination take place?" in the degree course “Medical Information Technology”
Dr. Oliver Licht
Leuphana University Lüneburg: lectures on toxicology and ecotoxicology (F3) and on REACH (F10 Law, International Regulations and Chemicals Management) in the professional Master's program "M.Sc. Sustainable Chemistry"
RWTH Aachen: lecture on regulatory toxicology and risk assessment in the degree course "M.Sc. Ecotoxicology"
Dr. Falko Partosch
Medical University of Vienna (Austria): lecture in the course module "Reproductive Toxicology" in the postgraduate program "Toxicology"
Dr. Gerhard Pohlmann
TRAIN Academy: lectures on the regulatory framework for medical devices, on standards for medical devices and on economic aspects in implant development in Module 5 (Medical devices) and on preclinical development of medical devices and on preclinical development of inhalers (best practice) in Module 8 (Pre-clinic) of the vocational training program “Translational Research and Medicine: From the Idea to the Product“
Dr. Bernhard Polzer
University of Regensburg: lectures on molecular oncology in the degree course “Molecular Medicine”; hands-on training in molecular oncology
Prof. Dr. Antje Prasse
Hannover Medical School: main lectures on internal medicine in the degree course "Human medicine"; seminar on pulmonological topics for interns in the degree course "Human medicine"; lectures on translational research in pulmonoloy within the REBIRTH/KFO311 Ph.D. student program
Prof. Dr. Tobias Pukrop
University of Regensburg: lectures and bedside teaching in the degree course “Human Medicine”; lectures on pathophysiology and molecular oncology in the degree course “Molecular Medicine”; hands-on training in molecular oncology
Ostbayerische Technische Hochschule: lectures on chemotherapy in the Master's program “Computer Science – study option Medical Information Technology”, course on the analysis and recording of medical processes
Priv.-Doz. Dr. Susanne Rittinghausen
University of Veterinary Medicine Hannover, Foundation: seminars in toxicological pathology
Dr. Anton Roß
Hamburg University of Applied Sciences: lectures in Good Manufacturing Practice (GMP)
Dirk Schaudien Ph.D.
University of Veterinary Medicine Hannover, Foundation: lectures and seminars in special and toxicological pathology
Dr. Stefanie Scheffler
Leuphana University Lüneburg: lectures in module F10 Law, International Regulations and Chemicals Management in the professional Master's program "M.Sc. Sustainable Chemistry"
Dr. Katherina Sewald
Hannover Medical School: lectures on allergy and asthma, analgesics, Parkinson's disease and schizophrenia in the degree courses “Biomedicine” and "Biochemistry"; laboratory course in biomedicine; laboratory course in biochemistry: immunology
RWTH Aachen: lectures on immunotoxicology in the vocational degree course Laboratory Animal Science M. Sc.”
TRAIN Academy: lectures on immunotoxicology
Prof. Dr. Dr. Thomas Thum
Hannover Medical School: lectures in translational research; supervision of Bachelor, Master, Ph.D. and StrucMed students
Imperial College London (UK), National Heart and Lung Institute: lectures in molecular medicine
Dr. Henning Weigt
TRAIN Academy: lectures on “Preclinical development, phases, costs, and quality assurance”
Dr. Christian Werno
University of Regensburg: lectures on pathology and molecular oncology in the degree course “Molecular Medicine”; hands-on training in molecular oncology
Ostbayerische Technische Hochschule Regensburg: seminar "How does metastatic dissemination take place?" in the degree course “Medical Information Technology”
Prof. Dr. Lena Wiese
Goethe University Frankfurt: lectures on databases and data challenges; seminar on database management systems
Prof. Dr. Holger Ziehr
Technische Universität Braunschweig: lectures on applied and technical biochemistry
Ariane Zwintscher
Leuphana University Lüneburg: lectures in module F10 Law, International Regulations and Chemicals Management in the professional Master's program "M.Sc. Sustainable Chemistry"
Fraunhofer Institute for Toxicology and Experimental Medicine