Sonntag, 18. Mai 2025
Thematic Poster Session: A32 IT’S NOT EASY BEING WHEEZY: ASTHMA AND COPD CLINICAL STUDIES
11:30–13:15 Uhr
(Poster Board # P1403) „Safety and Tolerability of Intranasal OM-85 (OM-85-IN) in Healthy Volunteers and Patients With Mild Allergic Asthma: A Phase 1a/1b Randomized, Double-Blind, Placebo-Controlled Study“
Autor*innen: Jens M. Hohlfeld, Caterina Sansone, Pauline Pluviaud, Edouard Baulier PhD, Thomas Kayser, Philipp Badorrek, Lorenz Lehr
Mini Symposium: A21 UNCOVERING THE IMMUNE LANDSCAPE AND MOLECULAR DRIVERS OF LUNG CANCER: FROM CARCINOGENESIS TO TARGETED THERAPIES
9:15-11:15 Uhr
„Anti-PD-1 and Anti-CD39 Induce Respective CD8 T Cell and Macrophage Responses at the Patient-derived Ex Vivo Tumor-border“
Autor*innen: Tonia Bargmann, Sebastian Konzok, Renato Liguori, Maximilian Fuchs, Charline Sommer, Dirk Schaudien, Charlotte Schob, Stephan Halle, Christopher Werlein, Patrick Zardo, Lavinia Neuebert, Danny Jonigk, Fulvia Ferrazzi, Katherina Sewald, Susann Dehmel, Armin Braun
Montag, 19. Mai 2025
Poster Discussion Session: B30 ADVANCED MODALITIES TO UNCOVER PATHOPHYSIOLOGIC FEATURES IN COPD
9:15- 11:15 Uhr
(Poster Board # 921) „Effect of RLS-0071 on Airway Neutrophilia Following Inhaled Endotoxin Challenge Assessed by Chipcytometry“
Autor*innen: Christina Gress, Andreas Tillmann, Saskia Carstensen-Aurèche, Neel K. Krishna, Kenji Cunnion, Meike Müller, Jens M. Hohlfeld
Thematic Poster Session: B36 REPAIR MY BROKEN LUNGS
9:15-16:15 Uhr
(Poster Board # P545) „Change of Bronchoalveolar Lavage Proteome Following Segmental Lipopolysaccharide Challenge in Humans“
Autor*innen: Christina Gress, Meike Müller, Jens Hohlfeld
Thematic Poster Session: B73 EXPLORING LATE BREAKING MECHANISMS AND BIOMARKERS IN PULMONARY DISEASE PATHOGENESIS
11:30-13:15 Uhr
(Poster Board # P1387) Tankyrase Inhibition Demonstrates Anti-fibrotic Effects in Preclinical Pulmonary Fibrosis Models
Jo Waaler, Shoshy Alam Brinch, Ida Johnsen, Lena Willmer, Lavinia Neubert, Patrick Zardo, Hans-Gerd Fieguth, Christina Hesse, Mark Skarsfeldt, Stephen Jordan, Teresa Lucifora, Roberta Visone, Erika Ferrari, Paola Occhetta, Martin Frank Strand, Simon Rayner, Anita Wegert, Simon Cruwys, Stefan Krauss
Thematic Poster Session: B74 ADVANCED MODELS AND MOLECULAR SIGNATURES FOR UNDERSTANDING AND TREATING PULMONARY FIBROSIS
14:15-16:15 Uhr
(Poster Board # P1414) „Evaluating the Role of AMB-05X in Modulating Key Fibrotic Markers in Human Precision-cut Lung Slices“
Autor*innen: Christina Hesse, Valerie Beneke, Lena Willmer, Kevin Schmidt, Jan Fiedler, Kirk Johnson, Danny David. Jonigk, Patrick Zardo, Armin Braun, Katherina Sewald
Mini Symposium: B97 IT'S A VIRUS PARTY! FLU, PARAINFLUENZA, RSV, COVID, AND A LITTLE HIV
14:15-16:15 Uhr
„Inhaled Palmitoyl-conjugated Antiviral siRNA Reduces Human Parainfluenza Viral Infection In Vivo“
Autor*innen: Philippe Vollmer Barbosa, Fabian Röpken, Anna Zimmer, Maximilian Schinke, Josi Steinke, Katherina Sewald, Katharina Schwarz, Franziska Dahlmann, Adrian Schwarzer, Axel Schambach, Armin Braun
Poster Discussion Session: B108 INNOVATIVE INSIGHTS INTO LUNG INJURY: FROM INFLAMMATION TO BARRIER RESTORATION
14:15-16:15 Uhr
(Poster Board # 702) „Role of Tumor Necrosis Factor Superfamily Member 10 (TNFSF10) in SARS-CoV2-infection-associated Lung Damage“
Autor*innen: Irina K. Kuznetsova, Christina Malainou, Anna-Lena Ament, Marek Bartkuhn, Jochen Wilhelm, Olga Danov, Armin Braun, Istvan Vadasz, Susanne Herold
Dienstag, 20. Mai 2025
Thematic Poster Session: C67 MICROBIAL THREATS IN FOCUS: TRANSLATIONAL AND CLINICAL INSIGHTS INTO RESPIRATORY VIRAL INFECTIONS AND METAGENOMICS
9:15-16:15 Uhr
(Poster Board # P1562) „Advanced Test Models for Delivery and Therapeutic Window of Novel Inhalable RNA Therapies“
Autor*innen: Philippe Vollmer Barbosa, Franziska Dahlmann, Helena Obernolte, Dorothee Winterberg, Katherina Sewald, Sebastian Hook, Fabian Roepken, Josi Steinke, Anna Zimmer, Axel Schambach, Adrian Schwarzer, Armin Braun, Katharina Schwarz
Poster Discussion Session: C29 READING BETWEEN THE LINES IN INTERSTITIAL LUNG DISEASE
9:15-11:15 Uhr
(Poster Board # 921) „Stiffness Measurements in Human Lung Slices Can Evaluate the Therapeutic and Preventive Potentials of Anti-fibrotic Drugs“
Autor*innen: Jae Hun Kim, Lena Willmer, Klaudia Grieger, Niccole Schaible, Mery Marimoutou, Thomas Fabre, Matthew Lech, Katherina Sewald, Christina Hesse, Holger Behrsing, Ramaswamy Krishnan, Bela Suki
Mittwoch, 21. Mai 2025
Scientific Symposium: D6 PREDICTING STRUCTURE FUNCTION RELATIONSHIPS IN IPF
Session Chair: Katherina Sewald
Presentations:
8:20-8:34 Uhr: „The State of the Art in IPF Research: From Bench to Bedside and Back to Bench“
Antje Prasse
9:16-9:30 Uhr: „Multifactorial Biomarker Integration to Expand Preclinical Drug Research Against Fibrosis“
Christina Hesse
Mini Symposium: D98 TRACING THE SCAR IN INTERSTITIAL LUNG DISEASES
11:00-13:00 Uhr
„Molecular and Mechanical Biomarker Integration in a Preclinical Lung Model to Advance Anti-Fibrotic Therapies“
Autor*innen: Lena Willmer, Klaudia Maria Grieger, Jae Hun Kim, Kevin Schmidt, Jan Fiedler, Lavinia Neubert, Christopher Werlein, Patrick Zardo, Hans-Gerd Fieguth, Bela Suki, Armin Braun, Ramaswamy Krishnan, Katherina Sewald, Christina Hesse
Fraunhofer-Institut für Toxikologie und Experimentelle Medizin